Establishment and evaluation of animal model with methamphetamine poisoning / 法医学杂志
Journal of Forensic Medicine
;
(6): 282-285, 2009.
Artigo
em Chinês
| WPRIM
| ID: wpr-983489
ABSTRACT
Amphetamine-type stimulants (ATS) is the most widespread narcotics in the 21st century. The methamphetamine's intoxication mechanism, psychological dependence, drug resistance and therapeutic drug development are the hot spots in current research. Establishment of animal model with methamphetamine poisoning is the basic for the relative studies, the normalization and standardization of the animal model settles the foundation for methamphetamine's further research. This article reviews the animal model of methamphetamine poisoning in China and abroad, the brief history of the acute, subacute and chronic animal model of methamphetamine poisoning, as well as the principles and methods of the animal model establishment and its evaluation criteria. The necessity, significance and its scientific expansion of performing experimental research on the methamphetamine poisoning animal model are also discussed.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Comportamento Estereotipado
/
Comportamento Animal
/
Córtex Cerebral
/
Transtornos Relacionados ao Uso de Anfetaminas
/
Modelos Animais de Doenças
/
Toxicologia Forense
/
Estimulantes do Sistema Nervoso Central
/
Injeções Intraperitoneais
/
Metanfetamina
Limite:
Animais
/
Humanos
Idioma:
Chinês
Revista:
Journal of Forensic Medicine
Ano de publicação:
2009
Tipo de documento:
Artigo
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