The pathological observation of acute intoxication by Alangium Chinese in mice / 法医学杂志
Journal of Forensic Medicine
;
(6): 329-331, 2009.
Artigo
em Chinês
| WPRIM
| ID: wpr-983494
ABSTRACT
OBJECTIVE@#To investigate the pathological change of mice organ intoxicated by Alangium Chinese and its poisoning mechanism.@*METHODS@#Mice were intoxicated by gavage with extract of Alangium Chinese. Then the histopathologic examination was made for evaluating the pathological changes in the organs of the poisoned mice by HE staining.@*RESULTS@#The main pathological changes included alveolar hemorrhage, pulmonary interstitial hemorrhage, sinus hepaticus expansion and congestion, hepatocyte edema, subarachnoid hemorrhage, congestion and hemorrhage of other organs.@*CONCLUSION@#The main target organs or tissue of Alangium Chinese are the lungs, liver and vascular smooth muscle. There is correlation between the toxic effect and the dosage.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Encéfalo
/
Extratos Vegetais
/
Distribuição Aleatória
/
Doença Aguda
/
Raízes de Plantas
/
Hepatócitos
/
Testes de Toxicidade Aguda
/
Alangiaceae
/
Patologia Legal
/
Modelos Animais de Doenças
Limite:
Animais
Idioma:
Chinês
Revista:
Journal of Forensic Medicine
Ano de publicação:
2009
Tipo de documento:
Artigo
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