Expression of monocyte chemoattractant protein-1 in sudden death due to viral myocarditis and its medicolegal significance / 法医学杂志
Journal of Forensic Medicine
;
(6): 334-336, 2009.
Artigo
em Chinês
| WPRIM
| ID: wpr-983496
ABSTRACT
OBJECTIVE@#To explore the expression and significance of monocyte chemoattractant protein-1 (MCP-1) in myocardium in sudden death caused by viral myocarditis (VMC).@*METHODS@#To investigate the expression of MCP-1 in VMC sudden death group and control group using improved immunohistochemical technique and to compare the difference of the expression of MCP-1 between two groups with statistical method.@*RESULTS@#In VMC sudden death group, MCP-1 was positively expressed in 17 of 20 cases. While only 4 of the 20 cases in the control group showed a mildly positive expression sparsely in myocardium, and the rest cases were completely negative. The rate of positive expression of MCP-1 in VMC group was obviously higher than that of the control group (P<0.01).@*CONCLUSION@#The expression of MCP-1 detected by immunohistochemistry provides an objective morphologic evidence for the diagnosis of VMC sudden death in forensic pathology.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Autopsia
/
Coloração e Rotulagem
/
Imuno-Histoquímica
/
Estudos de Casos e Controles
/
Morte Súbita Cardíaca
/
Quimiocina CCL2
/
Patologia Legal
/
Miocardite
/
Miocárdio
Limite:
Adolescente
/
Adulto
/
Idoso
/
Criança
/
Criança, pré-escolar
/
Feminino
/
Humanos
/
Masculino
Idioma:
Chinês
Revista:
Journal of Forensic Medicine
Ano de publicação:
2009
Tipo de documento:
Artigo
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