Receptor antagonist of NMDA and animal models of schizophrenia / 法医学杂志
Journal of Forensic Medicine
;
(6): 443-446, 2009.
Artigo
em Chinês
| WPRIM
| ID: wpr-983523
ABSTRACT
Schizophrenia is one of the common mental diseases. Because the mechanism of the schizophrenia is significantly complicated, the cause is still unknown. N-methyl-D-aspartate receptor antagonist can simulate the positive and negative symptoms, as well as the cognitive disorder of schizophrenia. Thus it has been widely used to establish the animal models of schizophrenia. The relationship of the three blocking agents of ion channels (phencyclidine, MK-801, ketamine) and the establishment of schizophrenia animal models is reviewed in this article.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Fenciclidina
/
Esquizofrenia
/
Comportamento Animal
/
Encéfalo
/
Maleato de Dizocilpina
/
Receptores de N-Metil-D-Aspartato
/
Antagonistas de Aminoácidos Excitatórios
/
Transtornos da Consciência
/
Modelos Animais de Doenças
/
Ketamina
Limite:
Animais
/
Humanos
Idioma:
Chinês
Revista:
Journal of Forensic Medicine
Ano de publicação:
2009
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS