Concentration changes of potassium and hypoxanthine in vitreous humor of swine and its application to postmortem interval estimation / 法医学杂志
Journal of Forensic Medicine
;
(6): 9-21, 2011.
Artigo
em Chinês
| WPRIM
| ID: wpr-983616
ABSTRACT
OBJECTIVE@#To investigate the relationship between postmortem interval (PMI) and concentration changes of components in swine vitreous humor.@*METHODS@#Ninety-six porcine eyes from swine dying from acute massive hemorrhage, being randomly divided into 24 groups, were stored in dark situation, at temperature of (15 +/- 2) degrees C and humidity of (50 +/- 5)% for 2-96 hours separately. The vitreous humor was collected. Concentrations of K+, Na+, Cl- and hypoxanthine (Hx) were analyzed by automatic biochemical analyzer and ultra performance liquid chromatograph (UPLC). The data were statistically analyzed by SPSS software.@*RESULTS@#Linear regression analysis showed that concentrations of vitreous K+ and Hx were positively correlated with PMI(R2=0.767 and R2 = 0.793, respectively). Binary linear regression showed a higher correlation for K+ and Hx with PMI estimation (R2 = 0.866). PMI was not significantly correlated with vitreous Na+ and Cl- concentrations.@*CONCLUSION@#Vitreous K+ and Hx concentrations can be used as the objective markers for PMI estimation. The binary linear regression functions of vitreous K+ and Hx concentrations with PMI are more accurate for estimating the PMI.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Mudanças Depois da Morte
/
Potássio
/
Sódio
/
Suínos
/
Temperatura
/
Fatores de Tempo
/
Corpo Vítreo
/
Análise de Regressão
/
Cromatografia Líquida de Alta Pressão
/
Hipoxantina
Limite:
Animais
Idioma:
Chinês
Revista:
Journal of Forensic Medicine
Ano de publicação:
2011
Tipo de documento:
Artigo
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