Homer protein expression after focal brain contusion in rats / 法医学杂志
Journal of Forensic Medicine
;
(6): 409-412, 2011.
Artigo
em Chinês
| WPRIM
| ID: wpr-983689
ABSTRACT
OBJECTIVE@#To investigate Homer protein expression after focal brain contusion and explore the relationship between expression and injury time.@*METHODS@#Focal brain contusion in rats was established and Homer protein expression in brain at different injury intervals after contusion was detected by immunohistochemistry and Western blotting.@*RESULTS@#A small amount of Homer positive expression cells were detected in control group, sham operated group and experimental group (0.5 h after contusion). The amount of Homer positive expression cells increased after 3 h and reached peak 12 h after contusion. The amount of positive cells continued to decrease 1 d after contusion and to the base level 7 d after contusion. Homer protein expression based on immunohistochemistry and Western blotting had statistical difference among adjacent groups.@*CONCLUSION@#Expression of Homer protein near the focal contusion area shows time dependence after brain contusion in rats.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Coloração e Rotulagem
/
Fatores de Tempo
/
Encéfalo
/
Lesões Encefálicas
/
Imuno-Histoquímica
/
Proteínas de Transporte
/
Distribuição Aleatória
/
Western Blotting
/
Ratos Wistar
/
Contusões
Limite:
Animais
Idioma:
Chinês
Revista:
Journal of Forensic Medicine
Ano de publicação:
2011
Tipo de documento:
Artigo
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