Establishment of skin scald model in mice / 法医学杂志
Journal of Forensic Medicine
;
(6): 92-99, 2012.
Artigo
em Chinês
| WPRIM
| ID: wpr-983718
ABSTRACT
OBJECTIVE@#To establish the model of skin scald in mice for the study of skin thermal injuries.@*METHODS@#After anaesthetization mice were scalded in a 1 cm-diameter circle area on the central dorsum by boiling water at contact times 10s or 25s. The mice were sacrificed at 1, 3, 5, 7 and 10 days after scald. The skin samples were collected and analyzed by gross and histopathological examinations.@*RESULTS@#Deep II degree thermal injury involving full-thickness skin was observed in the 10s scald group. III degree thermal injury involving full-thickness skin and the dorsal skeletal muscle was observed in the 25 s scald group.@*CONCLUSION@#A mouse skin scald model is established which is stable and can be used on the skin thermal injury in future research.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Pele
/
Fatores de Tempo
/
Índice de Gravidade de Doença
/
Queimaduras
/
Distribuição Aleatória
/
Reprodutibilidade dos Testes
/
Modelos Animais de Doenças
/
Epitélio
/
Temperatura Alta
Limite:
Animais
Idioma:
Chinês
Revista:
Journal of Forensic Medicine
Ano de publicação:
2012
Tipo de documento:
Artigo
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