Progress on epigenetics applications in forensic science / 法医学杂志
Journal of Forensic Medicine
;
(6): 366-370, 2012.
Artigo
em Chinês
| WPRIM
| ID: wpr-983764
ABSTRACT
Epigenetics is the study of heritable changes in gene expression other than changes in the underlying DNA sequence. Such changes include DNA methylation, histone modification, chromatin remodeling, genomic imprinting, X chromosome inactivation and non-coding RNA regulation. Recent progresses on epigenetics open new possibilities in tackling these challenging problems in forensic science, including identification of fetal paternity testing in embryonic period, determination of the necessary allele in paternity testing, discrimination of identical twins, origination analysis of micro tissue, verification of forged DNA. This review focuses on epigenetics concept and its latest application in the field of paternity testing, age estimation, discrimination between the twins, identification of tissue of origin, and estimation of postmortem interval.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Gêmeos Monozigóticos
/
Expressão Gênica
/
Impressão Genômica
/
Metilação de DNA
/
Epigênese Genética
/
Ciências Forenses
/
Alelos
/
Epigenômica
Limite:
Humanos
Idioma:
Chinês
Revista:
Journal of Forensic Medicine
Ano de publicação:
2012
Tipo de documento:
Artigo
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