Allele-specific PCR and its application in forensic science / 法医学杂志
Journal of Forensic Medicine
;
(6): 282-287, 2014.
Artigo
em Chinês
| WPRIM
| ID: wpr-983921
ABSTRACT
Allele-specific polymerase chain reaction (AS-PCR) is a technique based on allele-specific primers, which can be used to analyze single nucleotide polymorphism (SNP) effectively including the transition, transversion and insertion/deletion polymorphism and has been exploited in the study of diseases research, molecular diagnosis, and forensic biological evidence. The article systematically reviews the principle, the detection methods, improvement of AS-PCR, and its research updates in the fields of autosome, Y chromosome and mitochondrial SNP, as well as its application in forensic science.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Polimorfismo Genético
/
Reação em Cadeia da Polimerase
/
Primers do DNA
/
Polimorfismo de Nucleotídeo Único
/
Ciências Forenses
/
Alelos
Limite:
Humanos
Idioma:
Chinês
Revista:
Journal of Forensic Medicine
Ano de publicação:
2014
Tipo de documento:
Artigo
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