Genetic polymorphism of nine non-CODIS STR loci in Hunan Province-based Chinese Han population / 法医学杂志
Journal of Forensic Medicine
;
(6): 441-445, 2014.
Artigo
em Inglês
| WPRIM
| ID: wpr-983946
ABSTRACT
OBJECTIVE@#To determine the allelic frequency distribution and genetic parameters of nine non-CODIS DNA index systems of the short tandem repeat (STR) loci (D2S1772, D6S1043, D7S3048, D8S1132, D11S2368, D12S391, D13S325, D18S1364, and GATA198B05).@*METHODS@#A total of 353 blood samples were collected, extracted, amplified, and analyzed from unrelated healthy individuals of Han nationality in Hunan Province, China.@*RESULTS@#One hundred and fourteen alleles were observed in the population with corresponding allelic frequencies ranged from 0.001 0 to 0.323 0. For all the nine non-CODIS STR loci, the observed genotypic data showed no significant deviations from the Hardy-Weinberg equilibrium. The Ho, He, PIC, DP, and PE of the studied non-CODIS STR loci ranged from 0.1080 to 0.1950, 0.8050 to 0.8920, 0.7700 to 0.8600, 0.9250 to 0.9660 and 0.6070 to 0.7800, respectively.@*CONCLUSION@#Nine non-CODIS STR loci have high degrees of polymorphisms, which may be useful in individual forensic identification and parentage testing in forensic practice.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Polimorfismo Genético
/
Etnicidade
/
China
/
Repetições de Microssatélites
/
Povo Asiático
/
Alelos
/
Frequência do Gene
/
Genética Populacional
/
Genótipo
Limite:
Humanos
/
Masculino
País/Região como assunto:
Ásia
Idioma:
Inglês
Revista:
Journal of Forensic Medicine
Ano de publicação:
2014
Tipo de documento:
Artigo
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