Application of Metabonomics in Substance Abuse Toxicology Research / 法医学杂志
Journal of Forensic Medicine
;
(6): 400-407, 2022.
Artigo
em Inglês
| WPRIM
| ID: wpr-984133
ABSTRACT
Abstrct Metabonomics is a relative discipline that develops after genomics and proteomics, and it is an important component of systems biology. It uses high-throughput and high-sensitivity instruments to perform qualitative and quantitative analysis of all metabolic components in specific biological samples under limited conditions and combines with multivariate statistics to analyze and process the data to obtain information about physiological, pathological or toxicological changes in organisms. In recent years, because of the complicated mechanism of substance abuse and the continuous emergence of new psychoactive substances, metabonomics is increasingly used in substance abuse research. Therefore, this article reviews the application of metabonomics of substance abuse in the toxic mechanism, the mechanism of addiction and the discovery of biomarkers.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Biomarcadores
/
Transtornos Relacionados ao Uso de Substâncias
/
Proteômica
/
Metabolômica
Limite:
Humanos
Idioma:
Inglês
Revista:
Journal of Forensic Medicine
Ano de publicação:
2022
Tipo de documento:
Artigo
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