Progress of Research on Tumor Extracellular Matrix and Discoidin Domain Receptor 1 / 肿瘤防治研究
Cancer Research on Prevention and Treatment
; (12): 800-807, 2023.
Article
em Zh
| WPRIM
| ID: wpr-984574
Biblioteca responsável:
WPRO
ABSTRACT
Tumor extracellular matrix (ECM) is the center component of tumor microenvironment (TME), ECM diversity constitutes the inherent heterogeneity of TME that contributes to tumor growth, dormancy, drug resistance, and metastasis. Discoidin domain receptor 1 is one of the ECM receptors that interact with multiple ECM ligands. It also regulates the occurrence and development of tumors. Accordingly, DDR1 plays an increasingly important role in the prevention, diagnosis, and treatment of cancer. In this review, we primarily summarize the research of ECM and its receptors with components, regulation, cell receptors, and signaling pathways in tumor progression.
Texto completo:
1
Índice:
WPRIM
Idioma:
Zh
Revista:
Cancer Research on Prevention and Treatment
Ano de publicação:
2023
Tipo de documento:
Article