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Study on application of CODIS loci to excluding paternity / 法医学杂志
Journal of Forensic Medicine ; (6): 86-88, 2001.
Artigo em Chinês | WPRIM | ID: wpr-984790
ABSTRACT
OBJECTIVE@#The study was carried out on application of CODIS loci (FGA, vWA, CSF1PO, TH01, TPOX, D3S1358, D5S818, D7S820, D8S1179, D13S317, D16S539, D18S51 and D21S11) in 100 cases of excluding paternity.@*METHODS@#The PCR amplified products of Profiler Plus and Cofiler amplification kit were injected into a capillary on the ABI PRISM 310 Genetic Analyzer. GeneScan software analyzed the collected data, which can then be imported into Genotyper software for genotyping of alleles.@*RESULTS@#In the group of Mother-Child-Alleged Father, more than 3 STR loci incompatibilities between alleged father and child were found in all observed cases, the mean incompatibility was 6.63; In the group of Alleged Father-Child, 94.0% of all cases observed was found more than 3 STR loci incompatibilities, the mean incompatibility was 5.01.@*CONCLUSION@#The results showed that CODIS loci had good application to excluding paternity, and the choice of hyperpolymorphic markers in investigation, which were valued by DP, H and PE, had direct relation with the augmentation of incompatibilities in excluding paternity.
Assuntos
Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Paternidade / DNA / Amplificação de Genes / Reação em Cadeia da Polimerase / Sequências de Repetição em Tandem / Alelos / Genótipo Limite: Adulto / Criança / Feminino / Humanos / Masculino Idioma: Chinês Revista: Journal of Forensic Medicine Ano de publicação: 2001 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Paternidade / DNA / Amplificação de Genes / Reação em Cadeia da Polimerase / Sequências de Repetição em Tandem / Alelos / Genótipo Limite: Adulto / Criança / Feminino / Humanos / Masculino Idioma: Chinês Revista: Journal of Forensic Medicine Ano de publicação: 2001 Tipo de documento: Artigo