Study of distribution and metabolism of methamphetamine in hair of guinea pig / 法医学杂志
Journal of Forensic Medicine
;
(6): 214-217, 2001.
Artigo
em Chinês
| WPRIM
| ID: wpr-984801
ABSTRACT
OBJECTIVE@#To study the distribution and metabolism of methamphetamine in the hair of guinea pig.@*METHODS@#Determination of methamphetamine and its metabolite amphetamine in hair was performed by GC/MS and GC/NPD. Concentration-time course of methamphetamine and amphetamine in hair of guinea were recorded. Relationship between hair color, administrated dose and drug concentration in hair were also discussed.@*RESULTS@#The concentration of amphetamine is higher than the concentration of methamphetamine in the hair of guinea administrated a single dose or seven doses of methamphetamine. The concentration of methamphetamine and amphetamine were significantly related with administration dose and the incorporation rate into white and brown hair is much poorer than that of black hair.@*CONCLUSION@#Administration methods, dose and the color of hair affect the concentration of methamphetamine and amphetamine.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Cor de Cabelo
/
Cobaias
/
Cabelo
/
Anfetamina
/
Metanfetamina
Limite:
Animais
Idioma:
Chinês
Revista:
Journal of Forensic Medicine
Ano de publicação:
2001
Tipo de documento:
Artigo
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