Application of OCT in the Forensic Pathological Diagnosis of Coronary Artery Atherosclerosis and Myocardial Infarction / 法医学杂志
Journal of Forensic Medicine
;
(6): 58-62, 2019.
Artigo
em Inglês
| WPRIM
| ID: wpr-984981
ABSTRACT
OBJECTIVES@#To investigate the value of optical coherence tomography (OCT) in the diagnosis of coronary atherosclerosis and myocardial infarction in forensic identification.@*METHODS@#OCT and hematoxylin-eosin (HE) examination were performed to examine the pathological samples of coronary artery and myocardial infarction in 5 cases of sudden coronary death. The morphological and local measurement indexes were compared.@*RESULTS@#In the OCT images, the layers of coronary artery could be distinguishably featured, and the atheroma plaques had a good morphological correspondence with HE slices. The normal myocardia in the OCT image showed weak light signals with high absorbance, while the fiber scar tissues in the myocardial infarction areas showed strong light signals with low absorbance. There were no significant differences on the fibrous cap thickness in coronary atherosclerotic plaques or intima-media thickness between the OCT images and the HE slices (P>0.05). In the OCT images, the optical densities of the old myocardial infarction areas (1 226.24±622.66) and those of normal myocardia (3 707.90±962.98) were significantly different ( P<0.05).@*CONCLUSIONS@#The OCT image has a good morphological consistency with HE slice, thus is expected to be the primary screening method for the forensic pathology examination of coronary artery atherosclerosis and myocardial infarction, which can help to improve the diagnostic accuracy.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Doença da Artéria Coronariana
/
Angiografia Coronária
/
Vasos Coronários
/
Tomografia de Coerência Óptica
/
Patologia Legal
/
Aterosclerose
/
Espessura Intima-Media Carotídea
/
Infarto do Miocárdio
Limite:
Humanos
Idioma:
Inglês
Revista:
Journal of Forensic Medicine
Ano de publicação:
2019
Tipo de documento:
Artigo
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