Research Progress on Chiral Separation Methods and Toxic Effects of Methamphetamine Enantiomers / 法医学杂志
Journal of Forensic Medicine
;
(6): 337-343, 2019.
Artigo
em Inglês
| WPRIM
| ID: wpr-985019
ABSTRACT
Methamphetamine (MAMP) is a kind of amphetamine-type stimulants (ATS) which contains one chiral carbon atom in its structure. Therefore a pair of enantiomers, S-(+)-MAMP and R-(-)-MAMP exist. R type and S type methamphetamines possess similar physicochemical properties, but has largely different pharmacological and toxic effects. S-(+)-MAMP is the main component of addictive drug "Ice" at present, seriously affecting human health and public safety. The separation analysis and mechanism of toxic effects discussions on MAMP are the current research focuses. This paper reviews the research progress of separation analysis methods and toxic effects of methamphetamine enantiomers to provide reference for forensic study and forensic practice.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Estereoisomerismo
/
Detecção do Abuso de Substâncias
/
Estimulantes do Sistema Nervoso Central
/
Metanfetamina
Limite:
Humanos
Idioma:
Inglês
Revista:
Journal of Forensic Medicine
Ano de publicação:
2019
Tipo de documento:
Artigo
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