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Research Progress on Human Age Estimation Based on DNA Methylation / 法医学杂志
Journal of Forensic Medicine ; (6): 109-114, 2020.
Artigo em Inglês | WPRIM | ID: wpr-985096
ABSTRACT
In forensic science practice, age is an important individual information, and one of the indicators to be considered first to depict features of the suspect. Recently, DNA methylation has become a research hotspot in age estimation because of its hig accuracy and stability. New progress has been made in specificity of DNA methylation sites, age estimation in multiple tissues, DNA methylation age estimation of minors, sensitivity of age estimation, forensic practical applications, etc. At the same time, several studies also established more accurate statistical modeling methods, eliminated differences between different detection platforms, found appropriate number of sites in models and analyzed the influence of environment and diseases. This review summarizes these to provide references.
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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Ilhas de CpG / Metilação de DNA / Genética Forense Limite: Humanos Idioma: Inglês Revista: Journal of Forensic Medicine Ano de publicação: 2020 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Ilhas de CpG / Metilação de DNA / Genética Forense Limite: Humanos Idioma: Inglês Revista: Journal of Forensic Medicine Ano de publicação: 2020 Tipo de documento: Artigo