Application and prospect of electrospinning in functional periodontal tissue regeneration / 中华口腔医学杂志

ABSTRACT

In the case of periodontitis, local microecological imbalance can cause a large number of plaque biofilm accumulations, leading to the destruction of periodontal tissue and attachment loss, which makes it particularly difficult for the periodontal regenerative healing. In order to overcome the clinical treatment dilemma of periodontitis, periodontal tissue regeneration therapy assisted by new biomaterials has become a hot topic in recent years, among which electrospinning biomaterials with good biocompatibility have attracted wide attention. In this paper, based on periodontal clinical problems, the importance of functional regeneration is presented and clarified. Besides, according to the application of electrospinning biomaterials reported in previous researches, their effects of promoting functional periodontal tissue regeneration are analyzed. In addition, the internal mechanism of periodontal tissue repair by electrospinning materials is discussed and the future research direction is also proposed, in order to provide a new strategy for clinical treatment of periodontal diseases.