Research progress on ribosomal proteins and their functions in diseases / 药学实践与服务
Journal of Pharmaceutical Practice and Service
; (12): 519-523, 2023.
Article
em Zh
| WPRIM
| ID: wpr-988632
Biblioteca responsável:
WPRO
ABSTRACT
Ribosomal proteins (RP) are important components of ribosomes and play key roles in ribosome biogenesis and protein translation. In addition, ribosomal proteins also possess many extra-ribosomal functions, such as regulation of gene expression, cell proliferation, differentiation, apoptosis, DNA repair, and many other cellular processes. The dysfunction of RP is closely related to the occurrence and development of various diseases including blood, metabolism, cardiovascular diseases and tumors, and RP might become potential therapeutic targets for a variety of diseases. The research progress on RP, including the basic functions of RP, extra-ribosomal properties, and the connections with human diseases were reviewed and their potential as biomarkers and therapeutic targets in diseases were discussed in this paper.
Texto completo:
1
Índice:
WPRIM
Idioma:
Zh
Revista:
Journal of Pharmaceutical Practice and Service
Ano de publicação:
2023
Tipo de documento:
Article