Unilateral transcranial magnetic resonance-guided focused ultrasound Pallidothalamic Tractotomy in X-linked Dystonia-Parkinsonism: A case report
Acta Medica Philippina
;
: 70-76, 2022.
Artigo
em Inglês
| WPRIM
| ID: wpr-988670
ABSTRACT
@#X-linked dystonia-parkinsonism (XDP) is an adult-onset debilitating neurodegenerative disorder presenting with motor and nonmotor symptoms. The treatment options for XDP are limited. We described a patient with XDP who underwent a unilateral transcranial magnetic resonance-guided focused ultrasound (tcMRgFUS) pallidothalamic tractotomy with a one-year follow-up. The patient reported an immediate improvement in his pain after the procedure. Compared to baseline, there was an improvement in his scores in the dystonia (31%), parkinsonism (35.1%), and activities of daily living (71%) subscales at 1-year follow up. The overall improvement at one year was 46%. There were no adverse events noted. Additional studies with larger sample size and follow-up would be needed to document its long-term safety and efficacy.
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Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Distúrbios Distônicos
/
Doenças Genéticas Ligadas ao Cromossomo X
Idioma:
Inglês
Revista:
Acta Medica Philippina
Ano de publicação:
2022
Tipo de documento:
Artigo
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