Two Cases of Allergic Reactions to Mesna which Imitate Malar Rash / 대한류마티스학회지
The Journal of the Korean Rheumatism Association
;
: 196-199, 2000.
Artigo
em Coreano
| WPRIM
| ID: wpr-9891
ABSTRACT
Hemorrhagic cystitis is potentially life-threatening sequellae of chemotherapy using oxazaphosphorine alkylating agents (cyclophosphamide and ifosfamide). Mesna contains a sulfhydryl group that is believed to bind acrolein within the urinary collecting system and reduce the hemorrhagic cystitis without affecting the chemotherapeutic potential. To date, about thirty cases of hypersensitivity or allergic reactions of the delayed and urticarial type associated with mesna have been reported. We reported two patients with systemic lupus erythematosus who developed facial rash and flushing associated with mesna which imitate malar rash.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Acroleína
/
Mesna
/
Ciclofosfamida
/
Cistite
/
Tratamento Farmacológico
/
Alquilantes
/
Exantema
/
Rubor
/
Hipersensibilidade
/
Lúpus Eritematoso Sistêmico
Limite:
Humanos
Idioma:
Coreano
Revista:
The Journal of the Korean Rheumatism Association
Ano de publicação:
2000
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS