Epidemic status and etiological mechanism analysis of pancreatic cancer / 国际生物医学工程杂志

ABSTRACT

Pancreatic cancer is a highly malignant tumor and remains one of the most lethal types of cancer at this stage. Patients with pancreatic cancer have poor 5-year survival rates because of the relatively insidious clinical symptoms of the disease and its more rapid ability to invade surrounding tissues. Trends in pancreatic cancer incidence and mortality rates vary widely around the world. To date, certain risk factors, such as genetic factors, age factors, diabetes, obesity, chronic pancreatitis, and immune escape, have been identified as contributing to the development of pancreatic cancer. However, at this stage, there are no clear recommendations for pancreatic cancer screening, and cancer antigen 19-9 can only be used to monitor treatment response and as an indicator of disease recurrence, so primary prevention of pancreatic cancer is of utmost importance. In this article, the current status of the pancreatic cancer epidemic and the progress of research on etiological mechanisms were reviewed.