Research progress of multiple MRI-based radiomics in glioma / 国际生物医学工程杂志

ABSTRACT

Imaging histology plays a key role in the diagnosis of tumors, prognostic assessment, and evaluation of tumor response to therapy. Multimodal magnetic resonance imaging (MRI) imaging histology can link the imaging histological presentation of a tumor to its molecular phenotype, offering greater advantages in the grading of gliomas and in the prediction and prognosis of treatment response. It utilizes conventional and advanced techniques to differentiate brain tumors from non-neoplastic lesions and can be used for the diagnosis of gliomas and the differentiation of gliomas from brain metastases. Semi-automated and automated tumor segmentation techniques have also been developed for the assessment of the recurrence of gliomas. In this review paper, the research progress in multimodal MRI imaging histology was reviewed, including the prediction of important molecular biological markers of glioma, graded diagnosis of glioma, differential diagnosis with brain metastases, and assessment of postoperative recurrence.