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Research progress in reversing multidrug resistance in colorectal cancer / 国际肿瘤学杂志
Journal of International Oncology ; (12): 42-46, 2023.
Artigo em Chinês | WPRIM | ID: wpr-989518
ABSTRACT
Multidrug resistance impacts negatively upon the curative effect of chemotherapy and prognosis in colorectal cancer. There is a growing body of studies trying to develop drugs to overcome multidrug resistance against its common targets, including ATP-binding cassette proteins, metabolic enzymes, apoptotic genes, signaling pathways and genetic material, among which P-glycoprotein inhibitors and drugs disrupting DNA are deeply developed. Developing new inhibitors or combining existing inhibitors with conventional treatment are hopeful ways to overcome multidrug resistance in colorectal cancer.

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Idioma: Chinês Revista: Journal of International Oncology Ano de publicação: 2023 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Idioma: Chinês Revista: Journal of International Oncology Ano de publicação: 2023 Tipo de documento: Artigo