Research progress of cancer-associated fibroblasts in tumor radiotherapy resistance / 国际肿瘤学杂志
Journal of International Oncology
;
(12): 227-230, 2023.
Artigo
em Chinês
| WPRIM
| ID: wpr-989548
ABSTRACT
Cancer-associated fibroblasts (CAFs) is considered as a key factor for the severely limited efficacy in tumor radiotherapy. CAFs, as the primary stromal cells in the tumor microenvironment, can lead to tumor radiotherapy resistance by secreting a series of pro-tumor cytokines and nutrients, inhibiting anti-tumor immune response and remodeling extracellular matrix. Some progress has been made in the study of targeted CAFs sensitization radiotherapy, but the relevant study system is still imperfect. Therefore, a systematic exploration of the role of CAFs in tumor radiotherapy resistance and CAFs targeted therapy strategies can provide a basis for improving the current status of tumor radiotherapy resistance.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Journal of International Oncology
Ano de publicação:
2023
Tipo de documento:
Artigo
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