Correlation between meconium-stained amniotic fluid and intrauterine infection / 中华实用儿科临床杂志

ABSTRACT

Fetal hypoxia has long been described as the main cause of meconium-stained amniotic fluid (MSAF). However, recent studies have reported the presence of a variety of pathogenic microorganisms in meconium and amniotic fluid, and even more bacterial species in MSAF.Clinical observations also revealed that MSAF was closely related to fetal-neonatal infection and perinatal infection of pregnant women.Shortly after birth, the fetuses with MSAF developed infectious symptoms or showed abnormalities in infection-related laboratory indicators.Therefore, intrauterine infection may be one major cause of MSAF.To further our understanding of the factors leading to MSAF will improve the clinical management and prognosis of infants.