Research progress on interleukin-10 receptor A in the pathogenesis of inflammatory bowel disease / 中国小儿急救医学
Chinese Pediatric Emergency Medicine
;
(12): 1003-1006, 2022.
Artigo
em Chinês
| WPRIM
| ID: wpr-990466
ABSTRACT
Inflammatory bowel disease(IBD) is a complex multifactorial disease characterized by chronic recurrent intestinal inflammation.The etiology of IBD has not yet been determined, and relevant studies have focused on the genetic susceptibility, immune response, intestinal microbiome and environmental factors of the host.Studies have found that interleukin-10 receptor A(IL-10RA)plays important roles in the pathogenesis of IBD.IL-10RA can not only affect the intestinal barrier, but also affect the intestinal immune system.Furthermore, the mutation of IL-10RA itself is highly correlated with very early-onset IBD.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Chinese Pediatric Emergency Medicine
Ano de publicação:
2022
Tipo de documento:
Artigo
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