Analysis of influencing factors of Helicobacter pylori infection in obese preschool children / 中国医师杂志

ABSTRACT

Objective:To explore and analyze the influencing factors of Helicobacter pylori (HP) infection in obese preschool children.Methods:From May 2020 to May 2022, 50 obese preschool children with HP infection and 50 obese preschool children without HP infection were prospectively selected from Tangshan Maternal and Child Health Hospital. We collected and collected basic data on two groups of children, including gender, age, eating habits, and family related information. Single factor analysis was used to screen for possible influencing factors of HP infection in obese preschool children, and logistic regression analysis was performed on the selected influencing factors.Results:Single factor analysis of variance showed that there were statistically significant differences in the prevalence of HP infection among obese preschool children of different ages, body mass index (BMI), sharing tableware, per capita monthly income of families, using public chopsticks, washing hands before meals, partial eating, habit of biting fingers, family population, binge eating, family history of HP infection, etc. (all P<0.05). Multivariate logistic analysis showed that BMI ( OR=1.576, 95% CI 1.119-2.221), shared tableware ( OR=1.317, 95% CI 1.018-1.702), per capita monthly income of households ( OR=1.330, 95% CI 1.021-1.733), no use of public chopsticks ( OR=1.408, 95% CI 1.019-1.945), washing hands before meals ( OR=1.206, 95% CI 1.041-1.397), habit of biting fingers ( OR=1.470, 95% CI 1.064-2.031), binge eating ( OR=1.443, 95% CI 1.004-2.074) and family history of HP infection ( OR=1.317, 95% CI 1.051-1.649) were the influencing factors of HP infection in obese preschool children (all P<0.05). Conclusions:BMI, shared tableware, per capita monthly income of families, failure to use public chopsticks, washing hands before meals, habit of biting fingers, binge eating, family history of HP infection, etc. are the influencing factors of HP infection in obese preschool children. If there are children with abnormal related factors, attention should be paid to them. If there are related infection symptoms, targeted interventions can be taken in time to prevent and control children′s HP infection.