Effect of polypharmacy on anticoagulant therapy in elderly patients with atrial fibrillation / 中华老年医学杂志

ABSTRACT

Atrial fibrillation(AF)is a prevalent arrhythmia in elderly patients.Such patients often have comorbidities and are subjected to polypharmacy, which may lower medication compliance and increase the risk of bleeding and cardiovascular events.These factors may also affect the efficacy of anticoagulant therapy.According to research, non-vitamin K antagonistic oral anticoagulants like Rivaroxaban, Apixaban, and Dabigatran are a safer and more effective option for anticoagulant therapy in elderly patients with atrial fibrillation compared to warfarin.Studying the impact of polypharmacy on anticoagulant therapy in elderly patients with atrial fibrillation can aid in the development of personalized treatment strategies and improve the prognosis of aged patients.