Progress in key technologies of artificial intelligence-assisted blood cell morphology examination / 中华检验医学杂志

ABSTRACT

Artificial intelligence-assisted blood cell morphology examination of blood cells is very promising in clinical applications. Because it can significantly improve work efficiency, reduce the burden of manpower, avoid subjectivism, and facilitate standardization. The main difficulties lie in several key technical links, such as image acquisition, image segmentation, cell identification, and classification, etc. In recent years, both hardware devices and software algorithms have made rapid progress, which has led to the important development of artificial intelligence auxiliary systems from digital image acquisition, white blood cell segmentation, cell feature extraction, and classification. Compared with the traditional machine learning, the application of deep learning technology in the morphological identification of blood cells is particularly worthy of attention. In addition, the continuous emergence of microscopic blood cell image databases also provides important support for the further development and improvement of various algorithms. Understanding the key technical progress of artificial intelligence-assisted blood cell morphology examination will help to promote its continuous development and better clinical application. In recent years, artificial intelligence technology has changed from "traditional machine learning" to "deep learning", which no longer relies on manual extraction of features, but on its ability to automatically extract data to achieve. Compared with the blood cell image database from foreign countries, the construction of domestic databases should be strengthened to minimize the gap between foreign databases.