Research progress on regulation of Staphylococcus aureus Ebh protein by ArlRS two-component system / 中国生物制品学杂志
Chinese Journal of Biologicals
;
(12): 1010-1013+1020, 2023.
Artigo
em Chinês
| WPRIM
| ID: wpr-996575
ABSTRACT
@#Staphylococcus aureusis a major cause of hospital and community acquired infection,which can express many kinds of cell wall-related and extracellular virulence factors,causing a variety of infectious diseases. Ebh protein is involved in the adhesion,aggregation and biofilm formation of Staphylococcus aureus,and thus closely related to its strong pathogenicity. The pathogenesis of Staphylococcus aureus is controlled collaboratively by different two-component signal transduction systems and transcriptional regulation factors,among which ArlRS is the key two-component system(TCS)necessary for the adhesion,biofilm formation and virulence. At the same time,ArlRS regulates Ebh protein through global regulation factor MgrA,thus affecting the role of Staphylococcus aureus in human infectious diseases. In this paper,the regulatory mechanism was reviewed.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Chinese Journal of Biologicals
Ano de publicação:
2023
Tipo de documento:
Artigo
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