Changes in hemodynamic parameters and regional myocardial perfusion measured by thermal diffusion probe from the infusion of norepinephrine during displacement of porcine beating heart / 대한마취과학회지
Korean Journal of Anesthesiology
;
: 479-484, 2008.
Artigo
em Coreano
| WPRIM
| ID: wpr-99670
ABSTRACT
BACKGROUND:
This study was done to evaluate the sole effect of norepinephrine on the regional myocardial perfusion during displacement of the porcine beating heart using thermal diffusion method.METHODS:
Thermal diffusion probe was inserted into the anterior myocardial wall during 20 procedures in 10 male pigs (30-35 kg). The measurements of regional myocardial perfusion and hemodynamic parameters were performed after complete instrumentation (baseline), after displacement of the beating heart anteriorly, and 5 and 15 minutes after norepinephrine infusion, titrated to restore baseline mean arterial pressure (MAP).RESULTS:
Norepinephrine infusion reversed the decrease in MAP and myocardial perfusion, caused by displacement of the beating heart (62 +/- 3% to 115 +/- 4% of baseline, P < 0.01; 41 +/- 5% to 125 +/- 4% of baseline, P < 0.05, respectively).CONCLUSIONS:
Restoration of MAP with norepinephrine infusion without any preload augmentation reversed deterioration in regional myocardial perfusion during displacement of the porcine beating heart.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Perfusão
/
Suínos
/
Norepinefrina
/
Deslocamento Psicológico
/
Difusão Térmica
/
Ortoaminobenzoatos
/
Pressão Arterial
/
Coração
/
Hemodinâmica
Limite:
Humanos
/
Masculino
Idioma:
Coreano
Revista:
Korean Journal of Anesthesiology
Ano de publicação:
2008
Tipo de documento:
Artigo
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