Delayed diagnosis of pituitary stalk interruption syndrome with severe recurrent hyponatremia caused by adrenal insufficiency
Annals of Pediatric Endocrinology & Metabolism
;
: 208-212, 2017.
Artigo
em Inglês
| WPRIM
| ID: wpr-99764
ABSTRACT
Pituitary stalk interruption syndrome (PSIS) involves the occurrence of a thin or absent pituitary stalk, hypoplasia of the adenohypophysis, and ectopic neurohypophysis. Diagnosis is confirmed using magnetic resonance imaging. Patients with PSIS have a variable degree of pituitary hormone deficiency and a wide spectrum of clinical manifestations. The clinical course of the disease in our patient is similar to that of a syndrome of inappropriate antidiuretic hormone secretion. This is thought to be caused by failure in the suppression of vasopressin secretion due to hypocortisolism. To the best of our knowledge, there is no case report of a patient with PSIS presenting with hyponatremia as the first symptom in Korean children. Herein, we report a patient with PSIS presenting severe recurrent hyponatremia as the first symptom, during adolescence and explain the pathophysiology of hyponatremia with secondary adrenal insufficiency.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Hipófise
/
Adeno-Hipófise
/
Neuro-Hipófise
/
Vasopressinas
/
Imageamento por Ressonância Magnética
/
Insuficiência Adrenal
/
Diagnóstico
/
Diagnóstico Tardio
/
Hiponatremia
/
Hipopituitarismo
Tipo de estudo:
Estudo diagnóstico
Limite:
Adolescente
/
Criança
/
Humanos
Idioma:
Inglês
Revista:
Annals of Pediatric Endocrinology & Metabolism
Ano de publicação:
2017
Tipo de documento:
Artigo
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