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Efficacy of Asenapine in Schizophrenia Resistant to Clozapine Combined with Electroconvulsive Therapy: A Case Report
Artigo em Inglês | WPRIM (Pacífico Ocidental) | ID: wprim-763562
Biblioteca responsável: WPRO
ABSTRACT
Schizophrenic patients resistant to antipsychotics are diagnosed as having treatment-refractory schizophrenia, and they are treated with clozapine. However, clozapine is sometimes combined with electroconvulsive therapy (ECT) if clozapine monotherapy fails. In this report, a severe treatment-refractory schizophrenic patient who did not respond to clozapine even with ECT, but who recovered with asenapine monotherapy, is presented. Asenapine, considered a serotonin spectrum dopamine modulator, is a new atypical antipsychotic with unique pharmacological features that is used not only for schizophrenia, but also for bipolar disorder. The unique features of asenapine may be effective for some treatment-refractory schizophrenic patients.
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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Recidiva / Esquizofrenia / Suicídio / Antipsicóticos / Transtorno Bipolar / Humanos / Dopamina / Serotonina / Clozapina / Eletroconvulsoterapia Idioma: Inglês Revista: Clinical Psychopharmacology and Neuroscience Ano de publicação: 2019 Tipo de documento: Artigo