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AJNR Am J Neuroradiol ; 41(10): 1800-1803, 2020 10.
Article in English | MEDLINE | ID: covidwho-690396


Since December 2019, a novel Severe Acute Respiratory Syndrome coronavirus 2 from China has rapidly spread worldwide. Although respiratory involvement is the mainstay of coronavirus disease 2019 (COVID-19), systemic involvement has recently drawn more attention. In particular, a number of recent articles have shed light on the nervous system as one of the possible targets. At our institution, we observed 15 patients with acute brain vascular manifestations; most interesting, we had a higher prevalence of the posterior circulation acute impairment. In our series, 7 patients had acute posterior cerebral injury: 1, hemorrhagic posterior reversible encephalopathy syndrome; 5, posterior circulation ischemic stroke; and 1, parieto-occipital hemorrhagic stroke. On the basis of our evidence and previous basic science reports, we believe a common etiopathogenetic thread may connect ischemic/hemorrhagic events of the posterior circulation and posterior reversible encephalopathy syndrome in the setting of COVID-19.

Betacoronavirus , Coronavirus Infections/complications , Pneumonia, Viral/complications , Posterior Leukoencephalopathy Syndrome/etiology , Stroke/etiology , Adult , Aged , Aged, 80 and over , COVID-19 , Female , Humans , Intracranial Hemorrhages/etiology , Male , Middle Aged , Pandemics , Posterior Leukoencephalopathy Syndrome/diagnostic imaging , SARS-CoV-2 , Stroke/diagnostic imaging , Tomography, X-Ray Computed , Young Adult