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1.
Stem Cells and COVID-19 ; : 1-234, 2022.
Article in English | Scopus | ID: covidwho-2027816

ABSTRACT

Stem Cells and COVID-19 presents up-to-date knowledge on the effect of hematopoietic and mesenchymal stem cells to combat SARS-CoV-2 infection in its diagnosis, treatment and prevention. In addition, the book critically discusses challenges, highlighting outstanding questions and future perspectives. Written by global experts in the field for both pre-clinical and clinical practitioners, this comprehensive book delves into how stem cells have a strong potential in developing better diagnostic, treatment and preventive strategies in SARS-CoV-2 infection. Both hematopoietic and mesenchymal stem cells are critical to better understand the response of immune system to coronavirus infection in both healthy and co-morbid conditions in the development of effective vaccines and immunotherapies. © 2022 Elsevier Inc. All rights reserved.

2.
Stem Cells and COVID-19 ; : 7-22, 2022.
Article in English | Scopus | ID: covidwho-2027795

ABSTRACT

COVID-19 (coronavirus disease-2019) has been identified as a serious respiratory infection by the SARS-CoV2 virus (severe acute respiratory syndrome coronavirus 2), was first reported in Wuhan, Hubei Province, China in December 2019. World Health Organization (WHO) declared COVID 19 as a pandemic on March 11, 2020 considering the exponential spread and unmanageable mortality. It continues currently as the utmost urgent/critical ailment of global public health. Moreover, the COVID-19 pandemic has not only affected global health scenarios but also has heavily burdened the economic, financial, political, educational, and other dimensions of humanity across the world. Monitoring the COVID 19 pathology reveals a potential respiratory infection followed by severe pneumonia like clinical observations with greater chances of microvascular injuries and multiorgan failures in worse scenario. The preexisting comorbidities including type II diabetes, cardiovascular diseases, hypertension, and older age are other major aggravating factors. Rather than other flu viruses, the intricate interplay of SARS-CoV2 virus with the immune system underlies the pathological manifestations in both symptomatic and asymptomatic patients. This chapter highlights the role of heterogenous immune cell population, cytokine storm, immune cell activation, and potential signaling pathways associated with COVID 19 infection that are greatly appreciated to evolve novel translational therapeutic interventions. © 2022 Elsevier Inc. All rights reserved.

3.
5th International Conference on Information Systems and Computer Networks, ISCON 2021 ; 2021.
Article in English | Scopus | ID: covidwho-1759111

ABSTRACT

Today's generation wants everything easier, faster and automatic. During this corona pandemic, health and safety of each and every individual, either who is traveling through flights or working at an airport is a big issue. Usually, when we go to an airport, we go through many checks, and before boarding the flight, the security check-in, our luggage bags are counted and tagged by the person working at the counter of the airport. The luggage bags are put on the conveyor belt and the person working at the counter has to count the luggage bags by himself, he has to stick the tags on the luggage bags. None of the airports provides the facility of automatic counting of the luggage bags and sticking tags on them. And during this COVID-19 pandemic, we should avoid touching maximum things. This research paper provides a new technique for the same and that in a smart way. In this research, we are providing a novel approach to create an automatic system which will help to make the airport a smart one with IOT sensors and devices. Smart Airport also provides the counting of the luggage bags, tagging of the luggage bags, checking the presence of metallic objects in the luggage bags in a single embedded system. This approach will help the human society in maintaining social distancing and help them to save their time. © 2021 IEEE.

4.
Gastroenterology ; 160(6):S-221, 2021.
Article in English | EMBASE | ID: covidwho-1598570

ABSTRACT

Introduction Traditional methods of addressing gastroenterology referrals involve giving the referred patient an in office clinic appointment and waiting until the appointment to make consultant recommendations. In September 2019 (prior to the COVID-19 pandemic), our institution started an e-consult system for gastroenterology referrals where every referral was reviewed by a gastroenterologist and decision was made to direct the patient to telemedicine visit or in office visit. We aim to compare the outcomes of this e-consult system with traditional referral response methods. Methods Retrospective cohort study comparing econsults with traditional methods. We randomly selected 350 referrals from September 2019 through January 2020 to form the e-consult cohort and 350 referrals from January 2018 through May 2019 to form the traditional methods cohort. Outcomes of primary interest were observed for one month after referral. Primary outcome was number of patients with emergency department (ED) visits and hospitalizations for primary gastroenterology complaints within 30 days of referral. Secondary outcomes included mean time to first consultant recommendations, endoscopies, and in-person appointments. First consultant recommendations are defined as the first instance of recommendations (such as labs, imaging, endoscopy, or verbal instruction to the patient or referring physician) by a gastroenterology provider pertaining to the referring question after initial referral. Results E-consults were associated with significantly fewer ED visits (4% vs 7.7%, P=0.036) and fewer hospitalizations (1.4% vs 4.3%, p=0.023) within 30 days of referral. E-consults resulted in significantly higher proportion referrals receiving consultant recommendations within 30 days (87% vs 39%, P<0.01). Recommendations were also made in significantly less time with e-consults (4.3 vs 42 days, P<0.01). E-consults were also associated with a greater proportion for endoscopy performed within 30 days (17% vs 4%, P<0.01). Endoscopies were able to be performed in significantly less time after referral with e-consults (61 vs 96 days, P<0.01). Conclusions Gastroenterology referrals seen with e-consults were associated with significantly fewer ED visits and hospitalizations within 30 days of referral when compared to traditional methods. E-consults were also associated with dramatically shorter wait time for consultant recommendations and endoscopies as well as decreased need for in-person clinic appointments. (Table Presented) (Table Presented)

5.
Open Dentistry Journal ; 15(1):310-314, 2021.
Article in English | EMBASE | ID: covidwho-1334853

ABSTRACT

COVID-19 (Coronavirus disease 2019) is a contagious infection caused by novel coronavirus SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2). This novel virus was publicly announced as an infectious pathogen by the “Chinese Centre for Disease Control and Prevention” on 8 January 2020. The World Health Organization named COVID-19 a pandemic crisis all over the world on March 11, 2020. Aged people and medically compromised people like patients with diabetes, cardiovascular disease, chronic respiratory disease, and cancer are the vulnerable populations for developing an illness. A guideline has been postulated and described in the form of a journey map to avoid exposure of dental health care professionals to COVID-19. This review provides a comprehensive outlook for the current pandemic situation, its origin, spread, and preventive measures to be utilized in general and in dental practice.

6.
Indian Journal of Transplantation ; 15(2):131-133, 2021.
Article in English | Web of Science | ID: covidwho-1332217

ABSTRACT

The National Organ and Tissue Transplant Organization (NOTTO) has previously published transplant-specific guidelines with reference to COVID-19.([1]) The mortality is higher in dialysis patients with COVID-19 (12%-30%) than posttransplant COVID-19 patients (11.3%) and both are higher than the general population (<2%) in India.([2-5]) With the resumption of the kidney transplant program in various parts of India, new issues are expected to occur. There is uncertainty, regarding the safety of performing kidney,([ 6-8]) liver,([9-12]) and lunge([13]) transplantation in a recipient recently recovered from COVID-19. At present, we have limited evidence-based information about safety and feasibility of kidney transplantation from living donors, who have recovered from COVID-19.([4]) Recently, Indian Multi-center cohort studies have reported successful kidney transplantation in recipients from living donors with a previous diagnosis of COVID-19.([15, 16])

7.
National Tax Journal ; 74(1):257-301, 2021.
Article in English | Web of Science | ID: covidwho-1313744

ABSTRACT

Taxing consumption in the digital economy poses unique challenges for fiscal authorities. Recent institutional reforms, such as states changing remittance rules for the sales and use tax following the Supreme Court decision in South Dakota v. Wayfair, were enacted to increase tax revenue collections and create a more neutral tax system. Although these reforms induced more remote vendors to remit taxes on a destination basis, the revenue gains were modest, consistent with most large online vendors remitting taxes prior to the reforms. Instead, following the recent large shock to online shopping from the COVID-19 pandemic, the shift to destination-based taxation has redistributed revenues between large and small local jurisdictions. Increased online shopping raises revenue growth in small jurisdictions while contracting revenues in large jurisdictions. But Wayfair is not the end of the story: technological changes that induce new consumption patterns promise new challenges for fiscal authorities. Critical challenges for the next decades include limiting administrative and compliance costs of enforcing taxes in a digital world, determining filing thresholds, dealing with online marketplaces and facilitators, and taxing the consumption of digital services from two-sided platforms. With respect to digital services, we discuss whether consumption taxes should be imposed on both monetized platforms and nonmonetized platforms, such as social media, and the mechanisms for doing so.

9.
Clinical Cancer Investigation Journal ; 10(2):53-59, 2021.
Article in English | EMBASE | ID: covidwho-1227113

ABSTRACT

Severe acute respiratory syndrome coronavirus 2 as COVID-19 virus has affected the entire world and so to the cancer care and health-care facility. Cancer cervix is one of the common malignancies among women in developing and underdeveloped countries. Various challenges are being faced by patients and health-care providers to deliver optimal treatment under prescribed time frame. Faster delivery of whole treatment is desirable in the current pandemic. Overall treatment time in cancer cervix has prognostic value. Adoption of altered fractionation to delivered external beam radiation therapy could be a method for faster delivery of whole treatment. Altered fractionation such as hyperfractionation (HFX), hypofractionation, and accelerated fraction alone or with HFX has already been experimented for the past three decades. The total duration of treatment has been significantly reduced without addition of much toxicity. Few studies had also highlighted the feasibility of addition of chemotherapy to such fractionation schedule. However, prospective studies are still warranted to generate data to further support its use in the future.

10.
American Journal of Gastroenterology ; 115:S733-S733, 2020.
Article in English | Web of Science | ID: covidwho-1070089
11.
Indian Journal of Neurotrauma ; 17(1):1-2, 2020.
Article in English | EMBASE | ID: covidwho-957629
12.
International Journal of Research in Pharmaceutical Sciences ; 11(Special Issue 1):628-631, 2020.
Article in English | EMBASE | ID: covidwho-842779

ABSTRACT

In the wake of the current outbreak of novel Covid-19, which is now declared as a ’pandemic’ by the WHO, people around the globe have been dealing with a lot of difficulties. This virus had come into light in December 2019 and since then has only grown exponentially. Amongst the most affected are the ones who have been working extremely hard to eradicate it, which includes the hos-pitals, dental fraternity and the health-care workers. These people are finan-cially burdened due to limited practise. In the case of dentistry, to avoid the spread of the virus, only emergency treatments are being approved, and the rest of the standard procedures have been put on hold. In some cases, as the number of covid cases is rising, many countries are even trying to eliminate the emergency dental procedures to divert the finances towards the treatment of covid suffering patients. What we need to realise is that this is probably not the last time that we are facing such a situation. Instead of going down, we should set up guidelines with appropriate precautionary measures together with the use of standardised PPEs. The government should also establish specific poli-cies to support dental practices and other health-care providers. Together, we can fight this pandemic and come out stronger.

13.
International Journal of Research in Pharmaceutical Sciences ; 11(Special Issue 1):880-884, 2020.
Article in English | EMBASE | ID: covidwho-842778

ABSTRACT

Coronavirus disease 2019 (COVID-19) is an infectious disease caused by novel coronavirus resulting in severe acute respiratory syndrome coronavirus 2 (SARS-CoV). Dentistry is a dynamic profession that includes sophisticated treatment planning and a wide variety of treatment modalities ranging from conventional to advanced therapies. The infection is spread from droplets released during coughing, sneezing by the symptomatic or asymptomatic patient. Dentists are in continuous contact with saliva and blood while treating a COVID-19 positive patient. Universal body substance precautions remain as the front line for reasonable risk reduction. However, when dealing with a contagious agent that is spread by droplet contact, we need to recognize the need to manage our generation of aerosols as a judicious additional measure. For dental practices and hospitals in areas that are (potentially) affected with COVID-19, strict and effective infection control protocols are urgently needed. Journey maps play a useful role in conveying information in such a way, that is memorable, concise, and that creates a picture in a person mind. Till date vaccine against coronavirus is not introduced. Therefore the best option is to prevent exposure. This review aims at discussing the role of dentists in COVID-19, its spread through dental care setting status in India through Journey map.

14.
International Journal of Research in Pharmaceutical Sciences ; 11(Special Issue 1):462-468, 2020.
Article in English | Scopus | ID: covidwho-827268

ABSTRACT

Coronavirus disease 2019 (COVID-19) is a communicable infection caused by the novel coronavirus resulting in severe acute respiratory syndrome coron-avirus 2 (SARS-CoV). It was recognized to be a health crisis for the general population of international concern on 30th January 2020 and conceded as a pandemic on 11th March 2020. India is taking various measures to fight this invisible enemy by adopting different strategies and policies. To stop the COVID-19 from spreading, the Home Affairs Ministry and the health ministry, of India, has issued the nCoV 19 guidelines on travel. Screening for COVID-19 by asking questions about any symptoms, recent travel history, and expo-sure. India has been trying to get testing kits available. The government of India has enforced various laws like the social distancing, Janata curfew, strict lockdowns, screening door to door to control the spread of novel coronavirus. In this pandemic, innovative medical treatments are being explored, and a proper vaccine is being hunted to deal with the situation. Infection control measures are necessary to prevent the virus from further spreading and to help control the current situation. Thus, this review illustrates and explains the criteria provided by the government of India to the awareness of the public to prevent the spread of COVID-19. © 2020 Global Research Online. All rights reserved.

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