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1.
How COVID-19 is Accelerating the Digital Revolution: Challenges and Opportunities ; : 147-164, 2022.
Article in English | Scopus | ID: covidwho-20232313

ABSTRACT

Human Coronavirus (HCoV) or Novel Coronavirus (2019-nCoV) is probably a brand new version of coronavirus that belongs to Betacoronaviruses kind Human Coronaviruses, similar to the Severe Acute Respiratory Syndrome (SARS) coronavirus and Middle-East Respiratory Syndrome (MERS) coronavirus. China recorded the number one case of this virus in December 2019 at Wuhan, the capital town of Hubei province. By 27 March 2020, 10:00 CET, nearly 23,335 humans died out of 509,164 showed instances recorded throughout the world. By the give up of January 2020, China showed that the Novel Coronavirus (2019-nCoV) transmitted from one human to another. This studies pursuits to research a completely specific medicament called "Hinokitiol Copper Chelate” towards the large quantity 2019-nCoV Spike Glycoprotein with a unmarried receptor binding domain. This take a look at gives a super version for Hinokitiol Copper Chelate to be examined in silico towards 2019-nCoV Main Protease. © The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2022.

2.
How COVID-19 is Accelerating the Digital Revolution: Challenges and Opportunities ; : 1-209, 2022.
Article in English | Scopus | ID: covidwho-20232312

ABSTRACT

This book explores how digital technologies have proved to be a useful and necessary tool to help ensure that local and regional governments on the frontline of the emergency can continue to provide essential public services during the COVID-19 crisis. Indeed, as the demand for digital technologies grows, local and regional governments are increasingly committed to improving the lives of their citizens under the principles of privacy, freedom of expression and democracy. The Digital Revolution began between the late 1950s and 1970s and represents the evolution of technology from the mechanical and analog to the digital. The advent of digital technology has also changed how humans communicate today using computers, smartphones and the internet. Further, the digital revolution has made a tremendous wealth of information accessible to virtually everyone. In turn, the book focuses on key challenges for local and regional governments concerning digital technologies during this crisis, e.g. the balance between privacy and security, the digital divide, and accessibility. Privacy is a challenge in the mitigation of COVID-19, as governments rely on digital technologies like contact-tracking apps and big data to help trace peoples patterns and movements. While these methods are controversial and may infringe on rights to privacy, they also appear to be effective measures for rapidly controlling and limiting the spread of the virus. Next, the book discusses the 10 technology trends that can help build a resilient society, as well as their effects on how we do business, how we work, how we produce goods, how we learn, how we seek medical services and how we entertain ourselves. Lastly, the book addresses a range of diversified technologies, e.g. Online Shopping and Robot Deliveries, Digital and Contactless Payments, Remote Work, Distance Learning, Telehealth, Online Entertainment, Supply Chain 4.0, 3D Printing, Robotics and Drones, 5G, and Information and Communications Technology (ICT). © The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2022.

3.
Measur Sens ; 25: 100585, 2023 Feb.
Article in English | MEDLINE | ID: covidwho-2238685

ABSTRACT

Covid-19 is a novel pandemic disease with no potential vaccine treatment or medicine, the world is facing currently as of now. The death toll has increased to several lakhs and recovery rate is comparatively very less, was initially spotted in Wuhan (China). This spreads through close contact with people and socializing. The number of infected people varies with different parts of the world In our particular country India we are going through the lock down period which is the only vaccine to promote "social distancing" The hurdle arose due to the widespread of corona is major economy loss in combo with innocent lives. In this manuscript, we are visualizing the dataset which is publicly available to map, differentiate and separate the data in order to segregate the places that are most prone and perform basic regression to identify and predict the increasability of the counts from the dataset.

4.
Int. J. Pharm. Res. ; 2(12):1888-1892, 2020.
Article in English | ELSEVIER | ID: covidwho-681185

ABSTRACT

Novel Coronavirus (2019-nCoV) or Human Coronavirus (HCoV) could be a new coronavirus that belongs to Betacoronaviruses type Human Coronaviruses, just like the Middle-East Respiratory Syndrome (MERS) coronavirus and Severe Acute Respiratory Syndrome (SARS) coronavirus. Wuhan, the capital city of Hubei province, China recorded the primary case of this virus in December 2019. Until 27 March 2020, 10:00 CET, near 23,335 deaths were reported out of 509,164 confirmed cases recorded across the world. By the tip of January 2020, China confirmed that the COVID-19 transmitted from human to human. This study aims to check a completely unique medicament called “Remdesivir” (development code G S-5734) against the crystal structure of 2019-nCoV Main Protease. This study presents an ideal model for Remdesivir (anti-polymerase drug) to be tested in silico against 2019-nCoV Main Protease.

5.
Int. J. Pharm. Res. ; 2(12):1893-1900, 2020.
Article in English | ELSEVIER | ID: covidwho-681184

ABSTRACT

SBDD-Structure Based Drug Discovery is a vital tool for ‘In silico’ (pseudo-Latin term for in-silicon that refers to huge use of silicon in processor chips as an expression to mean computer simulation) study in medicine. It is a fast and cost-efficient drug discovery and optimization technique and has been proven to be more efficient than conservational techniques since it aims to recognize the molecular basis of a sickness and utilizes the understanding of 3-dimensional structure of the genetic target to design an efficient drug. In this paper we will focus on the virtual screening of Hinokitiol (β-Thujaplicin Copper Chelate docked docked against the profusion structure of 2019-nCoV Spike Glycoprotein with a Single Receptor-Binding domain to study and examine the action of Hinokitiol Copper Chelate as an anti-viral drug against the Spike Glycoprotein of nCoV-2019.

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