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16th Conference of the International Society of Indoor Air Quality and Climate: Creative and Smart Solutions for Better Built Environments, Indoor Air 2020 ; 2020.
Article in English | Scopus | ID: covidwho-1451200
2.
S Afr Med J ; 111(9): 841-848, 2021 07 20.
Article in English | MEDLINE | ID: covidwho-1404039

ABSTRACT

The increased use of heparin during the current COVID-19 pandemic has highlighted the risk of a rare but potentially serious complication of heparin therapy, viz. heparin-induced thrombocytopenia (HIT). This is a short review on the pharmacology of heparin and its derivatives, and the pathophysiology of HIT. Guidance on laboratory testing for and clinical management of HIT is presented in accordance with international guidelines. There are important similarities and differences between HIT and the new entity of vaccine-induced immune thrombotic thrombocytopenia, also known as thrombosis with thrombocytopenia syndrome, which clinicians need to be aware of.


Subject(s)
Anticoagulants/adverse effects , COVID-19 , Heparin/adverse effects , Thrombocytopenia/chemically induced , Anticoagulants/administration & dosage , COVID-19 Vaccines/administration & dosage , COVID-19 Vaccines/adverse effects , Heparin/administration & dosage , Humans , Thrombocytopenia/diagnosis , Thrombocytopenia/physiopathology
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