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J Family Med Prim Care ; 9(8): 4478-4479, 2020 Aug.
Article in English | MEDLINE | ID: covidwho-895497
Wellcome Open Res ; 5: 184, 2020.
Article in English | MEDLINE | ID: covidwho-808195


Background: India first detected SARS-CoV-2, causal agent of COVID-19 in late January 2020, imported from Wuhan, China. From March 2020 onwards, the importation of cases from countries in the rest of the world followed by seeding of local transmission triggered further outbreaks in India. Methods: We used ARTIC protocol-based tiling amplicon sequencing of SARS-CoV-2 (n=104) from different states of India using a combination of MinION and MinIT sequencing from Oxford Nanopore Technology to understand how introduction and local transmission occurred. Results: The analyses revealed multiple introductions of SARS-CoV-2 genomes, including the A2a cluster from Europe and the USA, A3 cluster from Middle East and A4 cluster (haplotype redefined) from Southeast Asia (Indonesia, Thailand and Malaysia) and Central Asia (Kyrgyzstan). The local transmission and persistence of genomes A4, A2a and A3 was also observed in the studied locations. The most prevalent genomes with patterns of variance (confined in a cluster) remain unclassified, and are here proposed as A4-clade based on its divergence within the A cluster. Conclusions: The viral haplotypes may link their persistence to geo-climatic conditions and host response. Multipronged strategies including molecular surveillance based on real-time viral genomic data is of paramount importance for a timely management of the pandemic.

Drone based Medical Service GPS based Tracking IOT ; 2020(Journal of Safety Science and Resilience)
Article in English | 2020/07/02/ | ID: covidwho-625529


With the quick spread of pandemic disease, many individuals have lost their lives across different parts of the world. So, the need for a novel approach or model to overcome the problem becomes a necessity. In this paper, a mechanism is proposed called DBCMS (Drone Based Covid-19 Medical Service) for the safety of medical employees who are prone to Covid-19 infection. The proposed mechanism can effectively improve the treatment process of Covid-19 patients. Drones are nowadays commonly used in the field of medical emergency situations. The proposed model in this paper uses drone service to reduce the risk of infection to the doctors or other medical staff, thereby preventing the disease spread. This paper further assumes that the primary step is to isolate people at their home instead of admitting them to the hospitals, also called a situation of lockdown or curfew. Thus, in this way, the spread can be significantly reduced across the globe if DBCMS approach is implemented at cluster level.