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Article in English | Web of Science | ID: covidwho-1939154


Introduction: The present study aims to assess the knowledge and attitude among the patients attending a dental hospital in Bhubaneswar, Odisha, India. Materials and Methods: A cross-sectional questionnaire-based survey was conducted among the general population from July 2020 to September 2020. It included 205 patients attending the outpatient department of Kalinga Institute of Dental Sciences, Bhubaneswar. A self-structured 17 item questionnaire regarding antibiotic resistance was used to assess the knowledge and attitude of the patients. Data were entered into Microsoft Excel sheet and analyzed using SPSS version 25.0. Results: The present study comprised 47.3% males and 52.7% females. Comparison of the knowledge and attitude domain scores was made across the educational levels of the participants and a significant difference was observed in the attitude domain scores. Conclusion: The present study stresses on the dire need for educating the general public about the rational use of antibiotics, thereby reducing further abuse leading to a global problem. The following core competencies are addressed in this article: Medical knowledge, Systems-based practice, Practice-based learning and improvement.

Journal of Association of Physicians of India ; 69(10):17-23, 2021.
Article in English | Scopus | ID: covidwho-1469268


Background: There is more than twofold rise in prevalence of mucormycosis cases in India during the COVID-19 pandemic which needs to be evaluated. Aims: The study aimed to document the spectrum of cases of mucormycosis seen at our Institute during COVID-19 times. Methods: The study is a retrospective observational study carried out at our Institute from May 2021 to mid-June 2021. All patients with biopsy-proven mucormycosis were enrolled in the study. The patients were subjected to complete history taking, ophthalmological examination, and imaging studies. The patients were treated with a multidisciplinary approach with antifungal therapy as well as surgical intervention when needed. Results: Ten patients (n=10) were seen, with a mean age of 50.3 years. The major risk factors included recent use of steroids, uncontrolled diabetes, and CKD. The most common presentation was swelling of unilateral eye and ptosis, followed by loss of vision. Inflammatory marker (CRP) and d-dimer were raised at presentation in all cases. Imaging showed the spread of infection from paranasal sinus to orbit and brain via cavernous sinus, which was a poor prognostic factor. Intravenous Amphotericin-B was given to all patients for at least 4 weeks. Two patients were discharged after completion of treatment and mortality was seen in three patients. Conclusion: We present an array of COVID-associated-mucormycosis (CAM) cases from Eastern India. CAM is presenting with rhino-orbito-cerebral involvement. There is poor outcome with cerebral involvement and high incidence of adverse effects with deoxycholate formulation of amphotericin-B. The causal association of COVID-19 with mucormycosis needs to be unearthed but possible preventive role of anticoagulation should be evaluated. © 2021 Journal of Association of Physicians of India. All rights reserved.