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1.
Medicina (Argentina) ; 82(4):487-495, 2022.
Article in Spanish | EMBASE | ID: covidwho-1965451

ABSTRACT

Introduction: the information regarding characteristics and ventilatory results comparing the first (W1) and the second wave (W2) in Argentina are limited. The main objective of this study was to describe general characteristics and ventilatory variables in COVID-19 patients who required invasive mechanical ventilation (IMV) and compare differences between waves. Secondarily, factors associated with mortality in intensive care unit (ICU) were studied. Methods: We conducted a prospective observational cohort study that included patients older than 18 years infected with SARS-CoV-2 consecutively admitted to ICU with IMV between August 1, 2020, and June 30, 2021. We included 412 patients. Results: We found statistically significant differences (p < 0.001) in age [W1 64(55-72) vs W2 59 (50-66) years], presence of COPD [W1 n = 42 (19.8%) vs. W2 n = 13(6.3%)], plateau pressure [W1 27(25-30) cm H2 O vsW2 24 (22-27) cmH2O], driving pressure (ΔP) [W1 15 (13-17) cmH2 O vs. W2 12 (11-14) cm H2O] compliance [W1 40 mL/cmH2O (32-46) vs. W2 = 33 mL/cm H2O (27-40)];reintubation [W1 30.4% (n = 63/207) vs. W2 13.7% (n = 28/205)]. We identified as independent factors associated with mortality the following variables: age [OR 1.07(95% CI 1.05-1.09)], the ΔP in the first 24 hours [OR 1.19(95% CI 1.10-1.28)] and W2 [OR 1.81 (95% IC1.12-2.93);p = 0.015. Discussion: During W2 the patients were younger. It was possible to achieve ventilatory mechanics more adjusted to a protective ventilation strategy. In conclusion, in the patients studied, age and ΔP were independent predictors of mortality.

2.
Kinesiology ; 54(1):116-125, 2022.
Article in English | Scopus | ID: covidwho-1955415

ABSTRACT

In order to maintain physical fitness during the COVID-19 quarantine, we designed a short-term intervention with one body-weight exercise – burpees. Thus, the aim of this study was to understand level of feasibility and potential benefits of our protocol to different variables in young adults during the COVID-19 quarantine. An online 4-week intervention was administered to 13 young adults (age 22.5±1.39 years, weight 71.8±10.1 kg). The main phase of each session consisted of burpees, a calisthenics body-weight exercises. The training was administered daily. Data regarding quality of life (QoL), body composition, posture, heart rate variability (HRV), cardiovascular health, and strength were collected before and after the intervention period. Participants’ QoL significantly increased after four weeks (p=.025). Also, participants’ strength improved, assessed by the push-up test (p=.017). Systolic blood pressure showed no difference between the pre-and post-measures, while a significant reduction was found in diastolic blood pressure. The HRV assessment showed increased mean RR (p=.005) and RMSSD (p=.014) and decreased mean HR (p=.004) (in the time-domain). For the frequency-domain variables, no significant difference was found. No significant changes were noted in body composition, posture, handgrip strength and countermovement squat jump height. Our preliminary results suggest that the 4-week daily online burpees intervention is a feasible method that could improve QoL, upper body strength and HRV in young adults. This non-time-consuming approach could be easily administered to promote healthy living and counteract physical inactivity during COVID-19 restrictions thanks to its feasibility, short duration, and low cost. © 2022, University of Zagreb - Faculty of Kinesiology. All rights reserved.

3.
2021 XIX WORKSHOP ON INFORMATION PROCESSING AND CONTROL (RPIC) ; 2021.
Article in English | Web of Science | ID: covidwho-1909256

ABSTRACT

Air quality is assessed by determining criteria pollutant levels in the atmosphere. While the most significant measurements are ground based, satellite remote sensing is rising as a complementary technique to reveal spatial distribution of pollutants in the integrated tropospheric column. In this work we present a new CONAE's value-added monthly product of nitrogen dioxide (NO2) for South America, derived from the tropospheric NO2 column density estimated by TROPOMI/Sentinel5p (ESA) data. Dataset generation of monthly mean, median, standard deviation and quantity of data used per pixel, along with distribution formats of downloading and visualizing data, are explained in order to provide to different users their characteristics and access. In addition, a spatial and temporal analysis is made for the Buenos Aires, Santiago and Sao Paulo cities along with ground measurements, for the august 2018 to may 2021 period and on a monthly basis. For this matter, higher values of nitrogen dioxide were observed in wintertime for the three cities, due to a greater quantity of stagnation episodes. While satellite derived data follows the temporal profile of ground-based concentrations, Santiago was the city of higher levels and bigger contrast to the summer levels. COVID-19 pandemic restrictions to traffic circulation is also noticed in the diminishing of NO2 in the two datasets, as it was also reported in previous studies. The publication of this new dataset holds the objective of supporting air quality monitoring in South America, helping non specialized users to freely access to interoperational data.

4.
Int J Obes (Lond) ; 46(7): 1280-1287, 2022 07.
Article in English | MEDLINE | ID: covidwho-1751706

ABSTRACT

INTRODUCTION: The corona virus disease 2019 (COVID-19) pandemic forced most of the Italian population into lockdown from 11 March to 18 May 2020. A nationwide survey of Italian Clinical Nutrition and Dietetic Services (Obesity Centers or OCs) was carried out to assess the impact of lockdown restrictions on the physical and mental wellbeing of patients with obesity (PWO) who had follow-up appointments postponed due to lockdown restrictions and to compare determinants of weight gain before and after the pandemic. METHODS: We designed a structured 77-item questionnaire covering employment status, diet, physical activity and psychological aspects, that was disseminated through follow-up calls and online between 2 May and 25 June 2020. Data were analyzed by multiple correspondence analysis (MCA) and multiple linear regression. RESULTS: A total of 1,232 PWO from 26 OCs completed the questionnaires (72% female, mean age 50.2 ± 14.2 years; mean BMI 34.7 ± 7.6 kg/m2; 41% obesity class II to III). During the lockdown, 48.8% gained, 27.1% lost, while the remainder (24.1%) maintained their weight. The mean weight change was +2.3 ± 4.8 kg (in weight gainers: +4.0 ± 2.4 kg; +4.2% ± 5.4%). Approximately 37% of participants experienced increased emotional difficulties, mostly fear and dissatisfaction. Sixty-one percent reduced their physical activity (PA) and 55% experienced a change in sleep quality/quantity. The lack of online contact (37.5%) with the OC during lockdown strongly correlated with weight gain (p < 0.001). Using MCA, two main clusters were identified: those with unchanged or even improved lifestyles during lockdown (Cluster 1) and those with worse lifestyles during the same time (Cluster 2). The latter includes unemployed people experiencing depression, boredom, dissatisfaction and increased food contemplation and weight gain. Within Cluster 2, homemakers reported gaining weight and experiencing anger due to home confinement. CONCLUSIONS: Among Italian PWO, work status, emotional dysregulation, and lack of online communication with OCs were determinants of weight gain during the lockdown period.


Subject(s)
COVID-19 , Adult , COVID-19/epidemiology , COVID-19/prevention & control , Communicable Disease Control , Female , Humans , Life Style , Male , Middle Aged , Obesity/epidemiology , Obesity/psychology , SARS-CoV-2 , Surveys and Questionnaires , Weight Gain
5.
EuropePMC; 2021.
Preprint in English | EuropePMC | ID: ppcovidwho-317958

ABSTRACT

Solar UV$-$C photons do not reach Earth's surface, but are known to be endowed with germicidal properties that are also effective on viruses. The effect of softer UV$-$B and UV$-$A photons, which copiously reach the Earth's surface, on viruses are instead little studied, particularly on single$-$stranded RNA viruses. Here we combine our measurements of the action spectrum of Covid$-$19 in response to UV light, Solar irradiation measurements on Earth during the SARS$-$CoV$-$2 pandemics, worldwide recorded Covid$-$19 mortality data and our 'Solar$-$Pump' diffusive model of epidemics to show that (a) UV$-$B$/$A photons have a powerful virucidal effect on the single$-$stranded RNA virus Covid$-$19 and that (b) the Solar radiation that reaches temperate regions of the Earth at noon during summers, is sufficient to inactivate 63\perc of virions in open$-$space concentrations (1.5 x 103 TCID50$/$mL, higher than typical aerosol) in less than 2 min. We conclude that the characteristic seasonality imprint displayed world$-$wide by the SARS$-$Cov$-$2 mortality time$-$series throughout the diffusion of the outbreak (with temperate regions showing clear seasonal trends and equatorial regions suffering, on average, a systematically lower mortality), might have been efficiently set by the different intensity of UV$-$B$/$A Solar radiation hitting different Earth's locations at different times of the year. Our results suggest that Solar UV$-$B$/$A play an important role in planning strategies of confinement of the epidemics, which should be worked out and set up during spring$/$summer months and fully implemented during low$-$solar$-$irradiation periods.

6.
Optical Instrument Science, Technology, and Applications II 2021 ; 11876, 2021.
Article in English | Scopus | ID: covidwho-1526441

ABSTRACT

The inactivation or airborne pathogens inside closed spaces is a critical issue that raised overwhelmingly during the current SARS-CoV 2 pandemic. Among the different technologies to achieve air sanification, the ultraviolet germicidal irradiation is a trending technique, also due to the fast development of more and more effective ultra-violet LED sources, that are expected to replace the mercury vapor lamps in the next few years. The positioning of LEDs inside cavities with highly reflective surfaces permits an enhancement of the internal irradiance and the development of compact devices. Optical simulations, by means of ray tracing, are fundamental, since an accurate irradiance estimation in presence of multiple internal reflections, scattering, light leaks outside the cav-ity and the sources angular emission distribution is not possible with only analytical calculations. Ray tracing permits to model the spatial irradiance inside the cavity by varying the components parameters to maximize the inactivation rate as a function of the air flow field. We discuss, on the basis of the experience on several related projects, the advantages of using the numerical approach to simulate these devices, focusing the attention onto the critical parameters which must be controlled to retrieve a reliable estimation of the system performance. © COPYRIGHT SPIE. Downloading of the is permitted for personal use only.

7.
O'Toole, A.; Hill, V.; Pybus, O. G.; Watts, A.; Bogoch, II, Khan, K.; Messina, J. P.; consortium, Covid- Genomics UK, Network for Genomic Surveillance in South, Africa, Brazil, U. K. Cadde Genomic Network, Tegally, H.; Lessells, R. R.; Giandhari, J.; Pillay, S.; Tumedi, K. A.; Nyepetsi, G.; Kebabonye, M.; Matsheka, M.; Mine, M.; Tokajian, S.; Hassan, H.; Salloum, T.; Merhi, G.; Koweyes, J.; Geoghegan, J. L.; de Ligt, J.; Ren, X.; Storey, M.; Freed, N. E.; Pattabiraman, C.; Prasad, P.; Desai, A. S.; Vasanthapuram, R.; Schulz, T. F.; Steinbruck, L.; Stadler, T.; Swiss Viollier Sequencing, Consortium, Parisi, A.; Bianco, A.; Garcia de Viedma, D.; Buenestado-Serrano, S.; Borges, V.; Isidro, J.; Duarte, S.; Gomes, J. P.; Zuckerman, N. S.; Mandelboim, M.; Mor, O.; Seemann, T.; Arnott, A.; Draper, J.; Gall, M.; Rawlinson, W.; Deveson, I.; Schlebusch, S.; McMahon, J.; Leong, L.; Lim, C. K.; Chironna, M.; Loconsole, D.; Bal, A.; Josset, L.; Holmes, E.; St George, K.; Lasek-Nesselquist, E.; Sikkema, R. S.; Oude Munnink, B.; Koopmans, M.; Brytting, M.; Sudha Rani, V.; Pavani, S.; Smura, T.; Heim, A.; Kurkela, S.; Umair, M.; Salman, M.; Bartolini, B.; Rueca, M.; Drosten, C.; Wolff, T.; Silander, O.; Eggink, D.; Reusken, C.; Vennema, H.; Park, A.; Carrington, C.; Sahadeo, N.; Carr, M.; Gonzalez, G.; Diego, Search Alliance San, National Virus Reference, Laboratory, Seq, Covid Spain, Danish Covid-19 Genome, Consortium, Communicable Diseases Genomic, Network, Dutch National, Sars-CoV-surveillance program, Division of Emerging Infectious, Diseases, de Oliveira, T.; Faria, N.; Rambaut, A.; Kraemer, M. U. G..
Wellcome Open Research ; 6:121, 2021.
Article in English | MEDLINE | ID: covidwho-1450989

ABSTRACT

Late in 2020, two genetically-distinct clusters of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) with mutations of biological concern were reported, one in the United Kingdom and one in South Africa. Using a combination of data from routine surveillance, genomic sequencing and international travel we track the international dispersal of lineages B.1.1.7 and B.1.351 (variant 501Y-V2). We account for potential biases in genomic surveillance efforts by including passenger volumes from location of where the lineage was first reported, London and South Africa respectively. Using the software tool grinch (global report investigating novel coronavirus haplotypes), we track the international spread of lineages of concern with automated daily reports, Further, we have built a custom tracking website (cov-lineages.org/global_report.html) which hosts this daily report and will continue to include novel SARS-CoV-2 lineages of concern as they are detected.

8.
Clinical & Experimental Rheumatology ; 09:09, 2021.
Article in English | MEDLINE | ID: covidwho-1268948

ABSTRACT

OBJECTIVES: We aimed to assess the prevalence of SARS-CoV-2 infection among Behcet's syndrome (BS) patients, evaluating the possible association between demographic and clinical features and the risk of infection. Moreover, we aimed to evaluate the possible association between BS disease activity and treatment, and the risk of SARS-CoV-2 infection. METHODS: A survey was conducted on BS patients followed at the Behcet's Centre of the Careggi University Hospital, Florence, Italy. We further evaluated the possible association between BS disease activity and treatment, and the risk of SARS-CoV-2 infection. RESULTS: Out of 335 BS patients contacted, fourteen cases of SARS-CoV-2 were identified between April 1st, 2020 and February 9th, 2021, suggesting a prevalence of SARS-CoV-2 infection among BS patients of 4.2%, in line with the data of the general population in Italy (4.4%). When comparing clinical features between SARS-CoV-2 cases and matched SARS-CoV-2 negative BS patients, we found that the presence of different disease manifestations did not significantly differ between the two groups. SARS-CoV-2 cases and controls were also comparable in terms of immunosuppressive therapy, with the only exception of corticosteroids (71.4% vs. 35.7%, p=0.030), whose daily dose was significantly higher in cases than controls [5mg/day (IQR 0-10,) vs. 0 mg/day (IQR 0-5), p=0.005], suggesting that the right timing of usage and the more appropriate dosage of corticosteroid are a key question for the better management of these patients. CONCLUSIONS: Based on our results, patients with BS do not seem to be at a greater risk of SARS-CoV-2 infection or severe complications compared with the general population.

9.
Sci Sports ; 36(5): 430-432, 2021 Oct.
Article in English | MEDLINE | ID: covidwho-1187852
10.
Plant Biosystems ; : 1-17, 2021.
Article in English | Academic Search Complete | ID: covidwho-1242078

ABSTRACT

The aim of the study is to identify potential natural compounds against SARS-CoV-2 occurring in essential oils (EOs) following literature data attesting their anti-viral activity. The epidemic virus that started in December 2019 in Wuhan, China, has spread worldwide as a global pandemic. The interest in the development of drugs from natural products has increased greatly in recent decades. (EOs) have been studied over the centuries and are known to possess various pharmaceutical properties. Recent antiviral and silico methods are used to discover phyto-compounds, suitable for coronavirus treatment. To obtain this result we employed gas chromatography for the analysis of essential oils from Laurus nobilis, Pinus pinea, Pistacia palaestina, Juniperus oxycedrus, Juniperus excelsa, Pinus brutia, Cupressus sempervirens, Lavandula stoechas, Origanum syriacum, O. ehrenbergi, Salvia tribola, Satureja thymbra, Calamintha origanifolia, Feoniculum vulgare, Mentha longifolia, Cuminum cyminum and Pinpinella anisum. [ABSTRACT FROM AUTHOR] Copyright of Plant Biosystems is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

11.
Acta Medica Mediterranea ; 37(2):1269-1270, 2021.
Article in English | Scopus | ID: covidwho-1215809

ABSTRACT

Unforeseen COVID-19 pandemic paralysed the entire world and its normal function. Although governmental restrictions might help the spreading rate of infection throughout the lockdown, health related issues such as lack of physical activity and malnutrition are having a tremendous negative impact in the general population. COVID-19 and its effects on the lifestyle of population at the moment is considered as a “hot topic” and different affected areas are being highly investigated. Despite scientific recommendations on PA and healthy eating, we were somehow forced to stop engaging in physical activity, affecting and making more difficult body mass management, which still remains an area of interest for the scientific community. Considering the failure to fulfilling physical activity recommendations, using this editorial, we suggest to the scientific community on creating an illustrated and clear guidance for general population regarding healthy nutrition accompanied with exercises in such circumstances. © 2021 A. CARBONE Editore. All rights reserved.

12.
International Journal of Environmental Research & Public Health [Electronic Resource] ; 18(8):12, 2021.
Article in English | MEDLINE | ID: covidwho-1208578

ABSTRACT

Athletes' lifestyles have been dramatically affected by the coronavirus disease 2019 (COVID-19) pandemic. Since COVID-19 primarily affects the respiratory system and to a lesser degree the cardiovascular system, the goal of this study was to examine the effects of COVID-19-caused detraining on cardiorespiratory fitness (CRF) of recently recovered volleyball athletes. Sixteen experienced volleyball athletes (age 24 +/- 4.5 years) who were recently diagnosed and recovered from a COVID-19 infection volunteered to participate in this study and were tested for CRF and spirometry. Given that participants had only mild symptoms of infection, the primary focus of this study was on the effects of detraining on CRF. On average, the time to exhaustion was 9.4 +/- 1.4 min. VE, VCO<sub>2</sub>, RER and oxygen pulse increased, heart rate exceeded 90% of predicted values, and peak VO<sub>2</sub> values were typical for this level of athlete (44.1 +/- 3.4 mL/kg). Pulmonary function reflected in FVC, FEV1/FVC and MVV values were well above 80% of predicted values for each of the participants while electrocardiography revealed no ischemia, arrythmias or conduction and repolarization abnormalities were found in the tested subjects. Therefore, it can be concluded that participants experienced typical consequences of detraining. Due to a lack of CRF data prior to COVID-19 infection, we were unable to estimate the magnitude detraining had on CRF. Complete CRF assessment after COVID-19 infection in athletes can be useful for screening of residual myocardial and/or respiratory system damage for safe return-to-play decisions.

13.
Open Dentistry Journal ; 15:87-96, 2021.
Article in English | EMBASE | ID: covidwho-1159099

ABSTRACT

Aim: The aim of this study was to test an experimental approach involving the remote monitoring of orthodontic patients through the use of their smartphones. Background: Due to the COVID-19 emergency, dental offices were asked to stop elective treatments;suddenly orthodontic patients found themselves isolated at home, without the possibility of monitoring by their orthodontists. The use of telemonitoring via smartphones can be a quick way to recover the orthodontist-patient relationship, monitor and continue the treatment. Objective: The purpose of this study was to propose an innovative, simple and reliable approach for the remote management of orthodontic patients. Methods: 137 patients were contacted verbally by phone and via WhatsApp®;they were asked to send a set of photographs taken with their smartphone. They were asked to complete a questionnaire to evaluate the effectiveness of the approach. Descriptive statistics (frequency with percent) of questionnaire results and the presence of procedural errors while taking pictures were calculated. Correlations between different questionnaire answers were analyzed with the Chi-Square test. Variables with p < 0:05 were declared as significant. Results: The majority of patients considered that this approach was positive and they did not feel abandoned. Difficulties emerged from a technical point of view, that is, in terms of photoshoot, and part of the patients expressed perplexity regarding the fact that telemonitoring can replace completely an outpatient visit. Conclusion: The use of telemonitoring managed to recreate a relationship with the orthodontist, especially in emergency periods.

14.
American Journal of Obstetrics and Gynecology ; 224(2):S95-S96, 2021.
Article in English | Web of Science | ID: covidwho-1140978
15.
Revista De Ensino De Bioquimica ; 20(2):I-I, 2020.
Article in Portuguese | Web of Science | ID: covidwho-1094927
16.
Revista De Ensino De Bioquimica ; 18(1):I-IV, 2020.
Article in Portuguese | Web of Science | ID: covidwho-970324
17.
Human Movement ; 21(4):79-87, 2020.
Article in English | Scopus | ID: covidwho-823935

ABSTRACT

Purpose. With the coronavirus outbreak, the preventive measures include staying at home and isolation, increasing sedentary behaviours and risk for worsening of chronic diseases. To explore alternative forms of home-based physical activity, the study aim was to evaluate physiological (heart rate [HR], respiratory exchange ratio [RER], oxygen consumption [ O2], energy expenditure [EE], metabolic equivalent task [MET]) and psychological (session rating of perceived exertion [sRPE], enjoyment) parameters of real (Zumba® class [ZC]) and exergame (Zumba® Fitness Rush [ZFR]) activities in relation to sex. Methods. Overall, 12 female (age: 24.7 ± 0.9 years) and 8 male (age: 25.3 ± 2.1 years) college students randomly performed 2 experimental 60-min sessions, ZC and ZFR, during which HR (expressed as percentage of individual maximal HR [%HRmax]), O2, RER, MET and EE were measured. After each session, sRPE and Physical Activity Enjoyment Scale (PACES) were used to monitor exercise intensity and enjoyment, respectively. Results. Main effects for sex (p = 0.02) and modality (p 0.0001) emerged for %HRmax, with women showing higher values than men and ZC showing higher values than ZFR. EE presented main effects for sex (p 0.0001) and modality (p = 0.0002), with higher values in men and in ZC. Main effect (p = 0.0001) for modality emerged also for O2 and MET, with higher values in ZC regardless of sex. No significant differences were observed for RER, sRPE, or PACES. Conclusions. Although ZC elicited higher cardiovascular and metabolic responses, ZFR, classified as a moderate-to-vigorous activity, could be used to maintain regular physical activity in a safe home environment during the coronavirus crisis. © University School of Physical Education in Wroclaw.

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