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Preprint in English | EMBASE | ID: ppcovidwho-326899


A new SARS-CoV-2 variant of concern, Omicron (B.1.1.529), has been identified based on genomic sequencing and epidemiological data in South Africa. Presumptive Omicron cases in South Africa have grown extremely rapidly, despite high prior exposure and moderate vaccination coverage. The available evidence suggests that Omicron spread is at least in part due to evasion of this immune protection, though Omicron may also exhibit higher intrinsic transmissibility. Using detailed laboratory and epidemiological data from South Africa, we estimate the constraints on these two characteristics of the new variant and their relationship. Our estimates and associated uncertainties provide essential information to inform projection and scenario modeling analyses, which are crucial planning tools for governments around the world.

Journal of Health Care for the Poor and Underserved ; 32(3):1301-1311, 2021.
Article in English | Web of Science | ID: covidwho-1396185


Purpose. Pharmacists provide comprehensive medication reviews (CMRs) to address provider shortages in medically underserved rural areas/populations (MUA/P). Currently, there are no studies regarding the proportions of CMRs completed directly with patients (here called, beneficiaries) from MUA/Ps themselves, or with others such as caregivers or primary care providers. Methods. This retrospective study analyzed adults in 2018 who received a CMR from a telehealth pharmacist. Chi-square tests compared differences in the proportion of CMRs completed with beneficiaries versus others. Multivariable logistic regression determined predictors of CMRs completed with beneficiaries. Findings. Of 19,655 participants, most were female (68%) and had Spanish preferred language (43%). The following had a greater likelihood of CMR completion with beneficiaries: age 65-74 years;non-rural residents;mental health prescription. These variables had less likelihood of CMR completion with beneficiaries: rural areas;men;and presence of medication nonadherence. Conclusion. The expansion of pharmacist-delivered CMRs occurred successfully in MUA/Ps. Further work is warranted to investigate the longitudinal effect on health markers.