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Infectious Disease Management in Animal Shelters ; n/a(n/a):367-392, 2021.
Article in English | Wiley | ID: covidwho-1224956


Summary While feline coronaviruses (FCoV) are ubiquitous in cat populations, the incidence of feline infectious peritonitis (FIP) remains low;nonetheless, the disease can be devastating for cat owners and shelter personnel. FIP is often challenging to diagnose, affects highly adoptable kittens and young cats, and creates prognostic uncertainty for healthy siblings of affected cats. FCoV is an enteric pathogen of cats that is often endemic in shelters and other multi-cat environments. Infection with FCoV generally occurs through fecal-oronasal transmission, most commonly through shared litterboxes contaminated with the virus. In some cases, more virulent strains of FCoV result in more severe FECV-related disease or an increased likelihood of mutation to FIPV. In others, the stress or immune status of the host plays a role in both decreased immune response and increased levels of shedding.

Expert Rev Hematol ; 13(10): 1081-1092, 2020 10.
Article in English | MEDLINE | ID: covidwho-759836


INTRODUCTION: Many patients with inherited or acquired benign hematological disorders are at increased risk of developing severe complications from COVID-19. These patients, therefore, require specific advice regarding isolation and changes to their usual treatment schedules. Their disease can also be associated with significant burden, and they necessitate life-long and regular access to therapy, and regular follow-up consultations and hospital visits. The current COVID-19 pandemic is therefore presenting many challenges for these patients, their families, and health-care professionals. AREAS COVERED: This review provides an overview of the reported COVID-19 cases in the literature in patients with certain benign hematological disorders including thalassemia, sickle cell disease, hemophilia, immune thrombocytopenia, venous thromboembolism, and aplastic anemia. The review also outlines some recommendations on how to manage these patients if they are infected with SARS-CoV-2. To review the literature on benign hematological disorders and COVID-19, a bibliographic search was performed using PubMed for articles published between January 2020 and June 2020. EXPERT OPINION: International efforts must be made to continue reporting and better understanding the effects of SARS-CoV-2 infection in these patients and accordingly develop a set of recommendations to optimize the treatment of future infected patients.

Coronavirus Infections/complications , Hematologic Diseases/complications , Pneumonia, Viral/complications , Betacoronavirus/isolation & purification , COVID-19 , Coronavirus Infections/epidemiology , Coronavirus Infections/therapy , Disease Management , Health Personnel , Hematologic Diseases/therapy , Humans , Pandemics , Pneumonia, Viral/epidemiology , Pneumonia, Viral/therapy , SARS-CoV-2