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1.
Ear Hear ; 2022 Jul 14.
Article in English | MEDLINE | ID: covidwho-1931919

ABSTRACT

OBJECTIVES: To report the direct and indirect impact of coronavirus disease 2019 pandemic on the Universal Newborn Hearing Screening program of our institution (Azienda Ospedaliero Universitaria di Sassari). DESIGN: Monocentric retrospective study whose target population included all the newborns born in or referred to our hospital in 2019 and 2020. RESULTS: There is no statistically significant difference in time to retest or loss to follow-up rate between the 2 years considered (2019 to 2020). Referral rate is not higher for newborns born to severe acute respiratory syndrome coronavirus 2 polymerase chain reaction positive mothers. CONCLUSIONS: In relation to the analyzed variables, coronavirus disease 2019 seems to have a limited impact on our screening program. Severe acute respiratory syndrome coronavirus 2 did not behave as an audiological risk factor in our series.

2.
J Infect Dev Ctries ; 15(11): 1640-1645, 2021 11 30.
Article in English | MEDLINE | ID: covidwho-1572709

ABSTRACT

INTRODUCTION: To analyze the virus spread among Sassari Hospital staff in the first Covid-19 wave and the impact of the Swab Team, a multidisciplinary task force entitled of nasopharyngeal swab collection and testing. METHODOLOGY: Nasopharyngeal swabs from HCWs between March 6 and May 28 2020 are evaluated. RESULTS: 4919 SARS-CoV-2 tests were performed on 3521 operators. Nurses and doctors are the categories at highest risk. After the Swab Team institution, the average number of swabs raised from 47/day to 86/day (p = 0.007). Positive samples decreased from 18.6% to 1.7% (p < 0.0001). CONCLUSIONS: The Swab Team is effective in increasing the cases tested and in reducing the reporting time. Procedure standardization reduces the risk for all the subjects involved (no transmission among swab team members, nor during the sample collection).


Subject(s)
COVID-19/prevention & control , Medical Staff, Hospital , Occupational Diseases/prevention & control , Patient Care Team , SARS-CoV-2 , Specimen Handling , Adult , COVID-19/diagnosis , COVID-19/epidemiology , Female , Humans , Italy/epidemiology , Male , Middle Aged , Pandemics , Retrospective Studies
3.
Otolaryngol Head Neck Surg ; 164(2): 277-284, 2021 02.
Article in English | MEDLINE | ID: covidwho-1140418

ABSTRACT

OBJECTIVE: To describe a remote approach used with patients with voice prosthesis after laryngectomy during the COVID-19 pandemic and the resulting clinical outcomes in terms of voice prosthesis complications management, oncological monitoring, and psychophysical well-being. STUDY DESIGN: Prospective cohort study. SETTING: Otolaryngology Clinic of the University Polyclinic A. Gemelli, IRCCS Foundation. SUBJECTS AND METHODS: All patients with voice prosthesis who underwent laryngectomy followed by our institute were offered enrollment. Patients who agreed to participate were interviewed to inquire about the nature of the need and to plan a video call with the appropriate clinician. Before and 1 week after the clinician's call, patients were tested with the Hospital Anxiety and Depression Scale. Degrees of satisfaction were investigated with a visual analog scale. A comparison between those who accepted and refused telematic support was carried out to identify factors that influence patient interest in teleservice. RESULTS: Video call service allowed us to reach 37 (50.68%) of 73 patients. In 23 (62.16%) of 37 cases, the video call was sufficient to manage the problem. In the remaining 14 cases (37.83%), an outpatient visit was necessary. Participants who refused telematic support had a significantly shorter time interval from the last ear, nose, and throat visit than patients who accepted (57.95 vs 96.14 days, P = .03). Video-called patients showed significantly decreased levels of anxiety and depression (mean Hospital Anxiety and Depression Scale total score pre- vs post-video call: 13.97 vs. 10.23, P < .0001) and reported high levels of satisfaction about the service. CONCLUSION: Remote approach may be a viable support in the management of patients with voice prosthesis rehabilitation.


Subject(s)
COVID-19/epidemiology , Laryngeal Neoplasms/surgery , Laryngectomy/rehabilitation , Larynx, Artificial/adverse effects , Telemedicine , Triage , Adult , Aged , Aged, 80 and over , Anxiety/diagnosis , Anxiety/etiology , Anxiety/prevention & control , Depression/diagnosis , Depression/etiology , Depression/prevention & control , Female , Humans , Laryngeal Neoplasms/psychology , Laryngectomy/adverse effects , Laryngectomy/psychology , Larynx, Artificial/psychology , Male , Middle Aged , Patient Satisfaction , Prospective Studies , Treatment Outcome , Voice Training
4.
J Vestib Res ; 31(5): 381-387, 2021.
Article in English | MEDLINE | ID: covidwho-1081662

ABSTRACT

BACKGROUND: since the beginning of COVID-19 outbreak a growing number of symptoms and deficits associated with the new pathology have emerged, among them cochlear damage in otherwise asymptomatic COVID-19 patients has been described. OBJECTIVE: to investigate general and audiovestibular symptoms and sequelae in healed patients, and to seek for any sign of residual or permanent hearing or vestibular loss. METHODS: we reviewed the data coming from 48 Covid-19 patients whose nasopharyngeal swabs have turned negative, all employed at our facility, that opted in for a free screening of audiovestibular symptoms offered by our hospital after the aforementioned report was published. The screening included a tonal pure tone audiometry, a vHIT and SHIMP test, as well as a survey including known symptoms and audiovestibular symptoms. RESULTS: general symptoms as reported by our patients largely reflect what reported by others in the literature. 4 (8.3%) patients reported hearing loss, 2 (4.2%) tinnitus, 4 dizziness (8.3%), 1 spinning vertigo (2%), 1 dynamic imbalance (2%), 3 static imbalance (6.3%). Most audiovestibular symptoms have regressed. Thresholds at pure tone audiometry and vHIT gain were within normality range in all post-Covid-19 patients. CONCLUSIONS: even if some patients suffer from audiovestibular symptoms, these are mostly transitory and there is no clear evidence of clinically relevant persistent cochlear or vestibular damage after recovery.


Subject(s)
COVID-19 , Hearing Loss, Sensorineural , Audiometry, Pure-Tone , Humans , SARS-CoV-2 , Vertigo/diagnosis , Vertigo/etiology
5.
Infection ; 49(5): 1055-1060, 2021 Oct.
Article in English | MEDLINE | ID: covidwho-983887

ABSTRACT

Severe acute respiratory syndrome coronavirus 2 infection might induce a significant and sustained lymphopenia, increasing the risk of developing opportunistic infections. Mucormycosis is a rare but severe invasive fungal infection, mainly described in immunocompromised patients. The first case of a patient diagnosed with coronavirus disease (COVID-19) who developed a pulmonary mucormycosis with extensive cavitary lesions is here reported. This case highlights how this new coronavirus might impair the immune response, exposing patients to higher risk of developing opportunistic infections and leading to worse outcomes.


Subject(s)
COVID-19 , Invasive Fungal Infections , Mucormycosis , Opportunistic Infections , Humans , Mucormycosis/diagnosis , SARS-CoV-2
6.
Am J Otolaryngol ; 41(5): 102551, 2020.
Article in English | MEDLINE | ID: covidwho-525813

ABSTRACT

RT-PCR detection of SARS-CoV-2 mRNA on nasopharyngeal swab is the standard for diagnosing active Covid-19 disease in asymptomatic subjects and in symptomatic patients without the typical radiological findings. Nasopharyngeal swabbing appears a trivial procedure, still an inappropriate nasopharyngeal sampling, performed by untrained operators, can be a relevant cause of false negative findings with a clear negative impact on the effort to control the epidemic and, when PPE is not properly used, this can expose healthcare workers and patients to risks of contagion.


Subject(s)
Betacoronavirus/isolation & purification , Clinical Laboratory Techniques/methods , Coronavirus Infections/diagnosis , Nasopharynx/virology , Pneumonia, Viral/diagnosis , Specimen Handling/methods , COVID-19 , COVID-19 Testing , Clinical Laboratory Techniques/instrumentation , Humans , Pandemics , SARS-CoV-2 , Specimen Handling/instrumentation
7.
Otolaryngol Head Neck Surg ; 163(3): 459-461, 2020 09.
Article in English | MEDLINE | ID: covidwho-378045

ABSTRACT

Reverse transcriptase polymerase chain reaction (RT-PCR) detection of SARS-CoV-2 mRNA on nasopharyngeal swab is the standard for diagnosing active COVID-19 disease in asymptomatic cases and in symptomatic patients without the typical radiologic findings. For the present COVID-19 outbreak in Italy, we describe 4 symptomatic patients with negative RT-PCR results at the first nasopharyngeal swab, which became positive when collected a few hours later by an otolaryngologist. All the patients showed nasal obstruction. The present report suggests that inadequate nasopharyngeal sampling performed by untrained operators in the presence of nasal obstruction can be a relevant case of false-negative findings at RT-PCR, with a clear negative impact on the efforts to contain the current outbreak.


Subject(s)
Clinical Competence , Coronavirus Infections/diagnosis , Nasopharynx/virology , Pneumonia, Viral/diagnosis , Specimen Handling/methods , Aged , Betacoronavirus , COVID-19 , False Negative Reactions , Female , Humans , Italy , Male , Middle Aged , Nasal Obstruction/complications , Pandemics , Reverse Transcriptase Polymerase Chain Reaction , SARS-CoV-2
8.
Head Neck ; 42(7): 1560-1569, 2020 Jul.
Article in English | MEDLINE | ID: covidwho-327366

ABSTRACT

BACKGROUND: Objective data on chemosensitive disorders during COVID-19 are lacking in the Literature. METHODS: Multicenter cohort study that involved four Italian hospitals. Three hundred and forty-five COVID-19 patients underwent objective chemosensitive evaluation. RESULTS: Chemosensitive disorders self-reported by 256 patients (74.2%) but the 30.1% of the 89 patients who did not report dysfunctions proved objectively hyposmic. Twenty-five percentage of patients were seen serious long-lasting complaints. All asymptomatic patients had a slight lowering of the olfactory threshold. No significant correlations were found between the presence and severity of chemosensitive disorders and the severity of the clinical course. On the contrary, there is a significant correlation between the duration of the olfactory and gustatory symptoms and the development of severe COVID-19. CONCLUSIONS: Patients under-report the frequency of chemosensitive disorders. Contrary to recent reports, such objective testing refutes the proposal that the presence of olfactory and gustatory dysfunction may predict a milder course, but instead suggests that those with more severe disease neglect such symptoms in the setting of severe respiratory disease.


Subject(s)
Betacoronavirus , Coronavirus Infections/complications , Olfaction Disorders/diagnosis , Pneumonia, Viral/complications , Sensory Thresholds , Taste Disorders/diagnosis , Adult , Aged , Aged, 80 and over , COVID-19 , Cohort Studies , Female , Humans , Italy , Male , Middle Aged , Olfaction Disorders/virology , Pandemics , SARS-CoV-2 , Severity of Illness Index , Taste Disorders/virology , Young Adult
9.
Head Neck ; 42(6): 1252-1258, 2020 06.
Article in English | MEDLINE | ID: covidwho-133571

ABSTRACT

BACKGROUND: The first European case series are detecting a very high frequency of chemosensitive disorders in COVID-19 patients, ranging between 19.4% and 88%. METHODS: Olfactory and gustatory function was objectively tested in 72 COVID-19 patients treated at University Hospital of Sassari. RESULTS: Overall, 73.6% of the patients reported having or having had chemosensitive disorders. Olfactory assessment showed variable degree hyposmia in 60 cases and anosmia in two patients. Gustatory assessment revealed hypogeusia in 33 cases and complete ageusia in one patient. Statistically significant differences in chemosensitive recovery were detected based on age and distance from the onset of clinical manifestations. CONCLUSION: Olfactory and gustatory dysfunctions represent common clinical findings in COVID-19 patients. Otolaryngologists and head-neck surgeons must by now keep this diagnostic option in mind when evaluating cases of ageusia and nonspecific anosmia that arose suddenly and are not associated with rhinitis symptoms.


Subject(s)
Ageusia/diagnosis , Ageusia/epidemiology , Betacoronavirus , Coronavirus Infections/complications , Olfaction Disorders/diagnosis , Olfaction Disorders/epidemiology , Pneumonia, Viral/complications , Aged , COVID-19 , Cohort Studies , Female , Hospitalization , Humans , Italy , Male , Middle Aged , Pandemics , SARS-CoV-2 , Symptom Assessment , Time Factors
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