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Gazi Medical Journal ; 32(2):213-218, 2021.
Article in English | Web of Science | ID: covidwho-1257156


Objective: The aim of the study is to compare the differences between COVID-19 pneumonia and other viral pneumonia (OVP) in terms of demographic, clinical and radiological features. Methods: This retrospective cohort study was conducted in Gazi University Hospital between 11 March and 24 May 2020. Patients, admitted to the hospital with suspected COVID-19 infection aged >18 years and those who had pneumonia on chest computed tomography (CT) scan were evaluated. SARS-CoV-2 RT-PCR and multiplex PCR, for other respiratory viruses, were performed. Patients with a positive SARS-CoV-2 PCR were included in "COVID-19 pneumonia" group and those who had a positive result for any other respiratory viruses and two consecutive negative results for SARS-CoV-2 were included in the "OVP" group. Two groups were compared in terms of clinical, laboratory and chest CT findings. Results: Of the 63 patients included in the study, 45 had COVID-19 pneumonia and 18 had OVP. Cough, nasal congestion, sputum production and leukocytosis were more common in the OVP group while leukopenia was more common in the COVID-19 pneumonia (p<0.05). The distribution pattern of parenchymal lesions on chest CT was more likely to be predominantly peripheral and posterior in COVID-19 pneumonia compared to OVP. Bilateral involvement was also more frequent in COVID-19 group compared to OVP (p<0.05). Conclusion: Distinguishing COVID-19 pneumonia from OVP with clinical and laboratory findings is difficult. Chest CT findings such as peripheral and posterior distribution of the parenchymal lesions and bilateral involvement may help to differentiate COVID-19 pneumonia from OVP.

Gazi Medical Journal ; 31(2 A):251-254, 2020.
Article in Turkish | EMBASE | ID: covidwho-678098


The SARS-CoV-2, agent of the Coronavirus disease 2019 (COVID-19), is a member of the Coronaviridae family leading to severe acute respiratory illness. It is enveloped RNA virus. WHO declared the outbreak of Covid-19 as a pandemic on 11 February 2020. After the emergence of the outbreak in the world and in our country, COVID-19 virology laboratory has been designed and diagnostic tests have been established for the early diagnosis of the SARS-CoV-2. The routine diagnosis of COVID-19 is achieved by the detection of viral RNA in clinical samples using the nucleic acid amplification tests like real-time polymerase chain reaction (PCR). The rapid diagnosis during the early phases of the infection is critically important for the isolation of the patients and for the development of preventive measures to control the infection in the community. In this context, after the emergence of the pandemic, different diagnostic techniques (real-time PCR tests, rapid antibody tests, and ELISA tests) have been used for the early diagnosis of COVID-19 in our hospital. In this paper, we want to emphasize the role and importance of the medical laboratories for the diagnosis of SARS-CoV-2, for tracking of the patients, and for epidemiologic studies during COVID-19 pandemic.