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1.
PLoS ONE [Electronic Resource] ; 18(1):e0279879, 2023.
Article in English | MEDLINE | ID: covidwho-2197125

ABSTRACT

The current epidemiological status of the new coronary pneumonia epidemic in China is being explored to prevent and control the localized dissemination of aggregated outbreaks. This study analyzed the characteristics of new outbreaks of coronavirus disease 2019 (COVID-19) at three stages of aggregated outbreaks in Jilin Province, China, to provide a reference for the prevention and control of aggregated outbreaks. Case information were collected from all patients in Jilin Province from January 12, 2020 to the present. The epidemic was divided into three stages according to the time of onset. The first stage comprised 97 cases reported from January 12, 2020 to February 19, 2020, during which 17 aggregated outbreaks occurred. The second comprised 43 cases reported from April 25, 2020 and May 23, 2020, involving one aggregated outbreak. The third comprised 435 cases reported on January 10, 2021 and February 9, 2021, involving one aggregated outbreak. The relationship between aggregated and non-aggregated cases in the first phase of the outbreak and the difference between imported and local cases during the aggregated outbreak were assess using statistical analysis, and the differences in the baseline information between the three phases were analyzed. The incubation periods of the three phases were 10 days, 8 days, and 5 days. The number of aggregated epidemic events in Jilin Province tended to increase and then decrease over time. The clustered events in Jilin Province were divided into four categories: household contact (14 times, 51 cases);household contact and public places (one time, three cases);household contact, public places, and gatherings (one time, six cases);and household contact, public places, gatherings, and work (three times, 495 cases). Clustered events occurred mainly between January 22, 2020, and February 4, 2020. Among all cases in the first phase of the outbreak, the method of detection and the time from diagnosis to discharge were longer in aggregated cases than in non-aggregated cases, and that the source of infection and renewal cases were more frequent and more likely to be detected in the outpatient clinics during aggregated outbreaks than the imported cases. The second phase of the epidemic showed significant spatial variability (Moran's I<0, P<0.05). The third stage of the epidemic occurred in a higher proportion of individuals aged 50-90 years and within a shorter incubation period compared with the first two stages. The current focus of prevention and control of the COVID-19 epidemic in Jilin Province is to strictly implement the restrictions on gatherings and to perform timely screening and isolation of close contacts of infectious sources while strengthening the supervision of the inflow of people from outside the region. Simultaneously, more targeted prevention and control measures can be implemented for different age groups and occupations.

2.
J Med Radiat Sci ; 2023.
Article in English | Web of Science | ID: covidwho-2173093

ABSTRACT

INTRODUCTION: The COVID-19 pandemic caused by the coronavirus SARS-CoV-2 has resulted in a global healthcare crisis. The provision of computed tomography (CT) imaging services by radiology departments for COVID-19 patients poses multiple challenges. Consequently, it is important to explore the clinical need and indications for thoracic CT and whether they subsequently alter patient management. METHODS: We report our experience in this single-centre retrospective cohort study of all confirmed COVID-19 cases admitted during the peak of the 'Delta' variant wave in Australia, and who underwent a chest CT. Clinical indication and patient management plan pre- and post-CT were ascertained. RESULTS: A total of 92 out of 1403 patients who were admitted with COVID-19 underwent a thoracic CT (73 CT pulmonary angiogram (CTPA), 14 CT Chest and five high-resolution CT (HRCT) studies). 72.8% of studies were to evaluate for pulmonary emboli, 16.2% for assessment of COVID-19 pneumonia complications, 5.4% for tuberculosis and 6.5% for other indications. 21 (23%) of these studies resulted in a change in management with two patients having a major change in management (thrombolysis, CT-guided aspiration). Management was altered due to diagnosis of pulmonary embolism (PE), pneumonia, cryptogenic organising pneumonia and other reasons. Of 73 CTPA studies, 11 (15%) patients had evidence of PE. CONCLUSION: In our centre, thoracic CT in COVID-19 patients were predominantly for the evaluation of PE with other indications being for COVID-19 complications and other cardiopulmonary pathologies. 23% of studies subsequently altered patient management, suggesting there is good clinical need for CT chests for these indications.

3.
Chinese Medical Ethics ; 35(10):1137-1143, 2022.
Article in Chinese | Scopus | ID: covidwho-2145247

ABSTRACT

To explore the influencing factors of perceived stress among frontline nurses during COVID-1 9, and the role of positive psychological capital in anxiety sensitivity and stress perception, so as to provide evidence for reducing the perceived stress of frontline nurses. From December 2021 to January 2022, 475 frontline nurses from 8 hospitals in X city were investigated by general data questionnaire, positive psychological capital, anxiety sensitivity index and perceived stress scale. The results showed that there were significant differences in nurses’ perceived stress in age, working years, professional title and salary. Perceived stress was positively correlated with anxiety sensitivity, negatively correlated with positive psychological capital, and anxiety sensitivity was negatively correlated with positive psychological capital. Anxiety sensitivity can not only directly predict perceived stress, but also negatively affect perceived stress through positive psychological capital. Therefore, during the epidemic prevention and control in COVID-1 9, nurses can obtain effective stress coping strategies by strengthening their positive psychological capital, thus reducing their anxiety and perceived stress, and better providing high-quality nursing services for patients. © 2022, Editorial department of Chinese Medical Ethics. All rights reserved.

4.
Journal of Medical Imaging and Radiation Oncology ; 66(Supplement 1):31, 2022.
Article in English | EMBASE | ID: covidwho-2136557

ABSTRACT

Purpose: The COVID-19 pandemic caused by the coronavirus SARS-CoV-2 has resulted in a global health care crisis. The provision of CT imaging services by radiology departments for COVID-19 patients poses multiple challenges. Thus, the clinical indications and utility of thoracic CT, determined by whether it subsequently alters patient management, in COVID-19 patients is important to establish. Current literature is not well established specifically for the 'Delta' SARS-CoV-2 variant. Methods and Materials: This is a single tertiary hospital centre retrospective review of all consecutive confirmed COVID-19 cases admitted during the peak of the 'Delta' variant wave in Australia who underwent a chest CT. Clinical indication for chest CT and patient management plan pre and post CT were ascertained. Result(s): During this period, 1403 patients were admitted with COVID-19 and 92 patients underwent CT of the thorax, with 18 patients scanned urgently. There were 73 CTPA, 14 CT Chest and 5 HRCT studies. 20 patients were in ICU at the time of scan. Regarding the clinical indications for thoracic CT, 72.8% of studies were to evaluate for pulmonary emboli, 16.2% for assessment of COVID-19 pneumonia complications, 5.4% for tuberculosis and 6.5% for other indications. 21 (23%) of these studies resulted in a change in management with 2 patients having a major change in management (thrombolysis, CT guided aspiration) whilst 19 had minor changes. Of 73 CTPA studies, 11 (15%) patients had evidence of pulmonary embolism. 6 patients underwent a second chest CT for diverse reasons. Conclusion(s): In conclusion, 6% of patients in the cohort of COVID- 19 patients admitted to our centre during the Delta variant wave of COVID-19 in NSW, Australia underwent a CT of the thorax. In 23% of these patients, chest CT resulted in a change in management. 72.8% of chest CT scans were for the evaluation of possible pulmonary emboli. CT was not used for diagnosis or follow-up of COVID-19 in any of our patients.

5.
National Science Review ; 9(11), 2022.
Article in English | Web of Science | ID: covidwho-2123132

ABSTRACT

This is the first study to characterize post-COVID-19 syndrome and identify risk factors for clinical and psychological sequelae of COVID-19 in two distinct cohorts of patients in China. This cross-sectional study evaluated the long-term health effects of coronavirus disease 2019 (COVID-19) in Jianghan District (Wuhan, China). The results showed that 61.4% of COVID-19 patients reported at least one symptom and 8.8% had depressive symptoms at the 17-month follow-up. The proportion of patients with chest radiographic abnormalities in Fangcang shelter hospitals and designated COVID-19 hospitals was 31.6% and 41.1%, respectively, and the proportion of patients with impaired pulmonary diffusion capacity in these hospitals was 52.8% and 60.9%, respectively. Female sex (odds ratio [OR] = 1.48, 95% confidence interval [CI]: 1.16-1.88), severe disease (OR = 1.46, 95% CI: 1.01-2.10) and a higher number of initial symptoms (OR = 1.31, 95% CI: 1.23-1.40) were associated with the development of sequelae symptoms at 17 months. This study involving community-dwelling COVID-19 adults may help determine the long-term effects of COVID-19 during the first pandemic wave. Nonetheless, larger follow-up studies are needed to characterize the post-COVID-19 condition.

6.
Journal of Medical Pest Control ; 38(5):440-443, 2022.
Article in Chinese | Scopus | ID: covidwho-2056265

ABSTRACT

Objective To analyze the epidemiological characteristics of surveillance results of public health emergencies of communicable diseases in Shenzhen from 2016 to 2020. Methods The data of public health emergencies in Shenzhen from 2016 to 2020 were derived from National Public Health Emergency Reporting Management Information System, the occurrence characteristics of epidemic outbreak were analyzed by disease types, regions and institution types, and SPSS 22. 0 was used for statistical analysis. Results The events of COVID-19 reported in 2020 were excluded,a total of 233 public health emergencies of for communicable diseases were reported, with 6 271 cases and 2 deaths were reported in Shenzhen from 2016 to 2020. The attack rate was 3. 87%, and the fatality rate was 0. 03%. The highest prevalence rate was 5. 20% in 2018. There were 164 clustered epidemic events, accounting for 70. 39% of the total information related to public health emergencies, involving 7 types of communicable diseases. Chicken pox (100 incidents,3 565 cases) and infectious diarrhea (41 incidents, 1 491 cases) were the found to be the most common diseases, accounting for 60. 98% and 25. 00% of the total clustered epidemic events, respectively. There were 78. 45% of the clustered events of respiratory communicable diseases occurred in primary schools, and 58. 33% of the clustered events events of intestinal diseases occurred in kindergartens. The difference was statistically significant in the composition ratio of the two kinds of communicable diseases in kindergartens, primary schools, middle schools, high schools, colleges and universities and other places. Conclusion A comprehensive prevention and control strategy should be adopted. The comprehensive control strategies should be formulated from aspects including the reduction of population susceptibility, implementing of early reporting and school suspension measures, monitoring of epidemic strains, and strengthening of personal hygiene protection habits for communicable diseases with high risk among different populations. © 2022, Editorial Department of Medical Pest Control. All rights reserved.

7.
IEEE Network ; : 1-7, 2022.
Article in English | Scopus | ID: covidwho-2018975

ABSTRACT

COVID-19 has now been sweeping the whole world, and fundamentally affecting our daily life. An effective mechanism to further fight against COVID-19 and prevent the spread of this pandemic is to alert people when they are in the vicinity of areas with a high infection risk, yielding them to adjust their routes and consequently, leave these areas. Inspired by the fact that mobile communication networks are capable of precise positioning, data processing and information broadcasting, as well as are available for almost every person, in this paper, we propose a mobile network assisted Risk arEa ALerting scheme, named REAL, which exploits heterogeneous mobile networks to alert users who are in/near to the areas with high risks of COVID- 19 infection. Specifically, in REAL scheme, all base stations (BSs) periodically estimate their serving users' locations, which are then analyzed by macro BSs (MBSs) to identify risk areas. Next, each MBS transmits the information about risk areas to small BSs (SBSs), which in their turn adjust the beamforming direction to cover these areas and send alerts to users located therein. Simulation results validate the effectiveness of the proposed REAL scheme. In addition, some key challenges associated with implementing REAL are discussed at the end. IEEE

8.
Lancet ; 398(10314):1872-+, 2021.
Article in English | Web of Science | ID: covidwho-1535487
9.
Lancet Healthy Longevity ; 2(7):E436-E443, 2021.
Article in English | Web of Science | ID: covidwho-1337972

ABSTRACT

The 2030 Sustainable Development Goals agenda calls for health data to be disaggregated by age. However, age groupings used to record and report health data vary greatly, hindering the harmonisation, comparability, and usefulness of these data, within and across countries. This variability has become especially evident during the COVID-19 pandemic, when there was an urgent need for rapid cross-country analyses of epidemiological patterns by age to direct public health action, but such analyses were limited by the lack of standard age categories. In this Personal View, we propose a recommended set of age groupings to address this issue. These groupings are informed by age-specific patterns of morbidity, mortality, and health risks, and by opportunities for prevention and disease intervention. We recommend age groupings of 5 years for all health data, except for those younger than 5 years, during which time there are rapid biological and physiological changes that justify a finer disaggregation. Although the focus of this Personal View is on the standardisation of the analysis and display of age groups, we also outline the challenges faced in collecting data on exact age, especially for health facilities and surveillance data. The proposed age disaggregation should facilitate targeted, age-specific policies and actions for health care and disease management.

10.
American Journal of Respiratory & Critical Care Medicine ; 203(9):1070-1087, 2021.
Article in English | MEDLINE | ID: covidwho-1208352

ABSTRACT

Background: This document provides evidence-based clinical practice guidelines on the diagnostic utility of nucleic acid-based testing of respiratory samples for viral pathogens other than influenza in adults with suspected community-acquired pneumonia (CAP). Methods: A multidisciplinary panel developed a Population-Intervention-Comparison-Outcome question, conducted a pragmatic systematic review, and applied Grading of Recommendations, Assessment, Development, and Evaluation methodology for clinical recommendations.

11.
Lancet ; 397(10287):1807-1808, 2021.
Article in English | Web of Science | ID: covidwho-1242375
12.
Acta Medica Mediterranea ; 37(2):1147-1153, 2021.
Article in English | Scopus | ID: covidwho-1215806

ABSTRACT

Introduction: Few previous studies have been well described the details of the clinical and virological course of illness among discharged patients. The study aims to study the epidemiological and clinical features of discharged patients with SARS-CoV-2 infection in Changchun, Northeast China. Materials and methods: We included all discharged patients with SARS-CoV-2 infection from Changchun Infectious Hospital, China, as 9 March 2020. We extracted and collected on data of demographic characteristic, clinical features, chest computed tomography (CT) scan, laboratory result, and treatment from the electronic medical records. Exact epidemiological information was obtained from the investigation of patients or close contacts by investigators of at all levels of the Center for Disease Prevention and Control in Jilin Province. Results: Of the 43 discharged patient retrospective studied, 38 were mild novel coronavirus pneumonia, only one with critical ill case and no health workers were infected. The median age was 41.0 years, and 25 were male. All cases were infected by person-to-person transmission and the median incubation period from exposure to illness onset was 8.0 days. 22 patients had comorbidities. The most common symptoms at illness onset were fever, cough, expectoration, myalgia or fatigue, chest tightness, nasal congestion or sneezing. Median duration of illness onset to hospital admission and discharged was 6.0 days and 22.0 days, the median duration of viral shedding after illness onset was 19.0 days (IQR: 14-22). Conclusion: Patients were imported and cluster cases by person-to-person transmission and relatively mild in Changchun, China. Our findings further confirmed the prolonged viral shedding among patients. © 2021 A. CARBONE Editore. All rights reserved.

13.
Open Access Macedonian Journal of Medical Sciences ; 8(T1):574-597, 2020.
Article in English | Scopus | ID: covidwho-1082569

ABSTRACT

BACKGROUND: Accumulated evidence revealed that male was much more likely to higher severity and fatality by SARS-CoV-2 infection than female patients, but few studies and meta-analyses have evaluated the sex differences of the infection and progression of COVID-19 patients. AIM: We aimed to compare the sex differences of the epidemiological and clinical characteristics in COVID-19 patients;and to perform a meta-analysis evaluating the severe rate, fatality rate, and the sex differences of the infection and disease progression in COVID-19 patients. METHODS: We analyzed clinical data of patients in Changchun Infectious Hospital and Center, Changchun, Northeast China;and searched PubMed, Embase, Web of Science, and Cochrane Library without any language restrictions for published articles that reported the data of sex-disaggregated, number of severe, and death patients on the confirmed diagnosis of adult COVID-19 patients. RESULTS: The pooled severe rate and fatality rate of COVID-19 were 22.7% and 10.7%. Male incidence in the retrospective study was 58.1%, and the pooled incidence in male was 54.7%. CONCLUSION: The pooled severe rate in male and female of COVID-19 was 28.2% and 18.8%, the risky of severe and death was about 1.6folds higher in male compared with female, especially for older patients (> 50 y). © 2020 Zhijun Li, Lina Feng, Wenyu Cui, Jian Zhang, Yingxin Huang, Yunhong Zhao, Fei Teng, Donglin Wu, Bonan Cao, Hui Wang, Liquan Deng, Qiong Yu.

14.
Iranian Red Crescent Medical Journal ; 22(10), 2020.
Article in English | EMBASE | ID: covidwho-958619

ABSTRACT

Introduction: In December 2019, a new type of pneumonia named coronavirus disease 2019 (COVID-19) was reported in Wuhan, Hubei province, China. The present study aimed to report the case of a patient with COVID-19 and comorbid pulmonary tuberculosis, on which there have been no relevant reports hitherto. Case Presentation: The case was a 47-year-old female patient with COVID-19 positive pharyngeal swabs. She did not suffer from fever, coughs, or difficulties in breathing. The patient was diagnosed with COVID-19 and pulmonary tuberculosis based on her epidemiological history, routine blood test, imaging findings, and COVID-19 nucleic acid test results. It should be noted that contact and droplet precautions were implemented for this patient. The administrated treatments for her included antiviral, anti-tuberculosis, and liver protection treatments. The patient did not complain about discomfort and her condition was stable. Conclusion: The COVID-19 and comorbid tuberculosis were suspected;however, epidemiological history, clinical presentation, laboratory tests, and imaging examinations must be combined to make a comprehensive diagnosis. Moreover, prompt quarantine and treatment measures should be implemented as well.

16.
Zhonghua Jie He He Hu Xi Za Zhi ; 43(0): E007, 2020 Feb 08.
Article in Chinese | MEDLINE | ID: covidwho-480
17.
Zhonghua Jie He He Hu Xi Za Zhi ; 43(0): E002, 2020 Feb 05.
Article in Chinese | MEDLINE | ID: covidwho-309

ABSTRACT

The recent outbreak of respiratory illness in Wuhan, China is caused by a novel coronavirus, named 2019-nCoV, which is genetically close to a bat-derived coronavirus. 2019-nCoV is categorized as beta genus coronavirus, same as the two other strains - severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome coronavirus (MERS-CoV). Antiviral drugs commonly used in clinical practice, including neuraminidase inhibitors (oseltamivir, paramivir, zanamivir, etc.), ganciclovir, acyclovir and ribavirin, are invalid for 2019-nCoV and not recommended. Drugs are possibly effective for 2019-nCoV include: remdesivir, lopinavir / ritonavir, lopinavir / ritonavir combined with interferon-ß, convalescent plasma, and monoclonal antibodies. But the efficacy and safety of these drugs for 2019-nCoV pneumonia patients need to be assessed by further clinical trials.

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