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1.
Gastroenterology ; 162(7):S-1006, 2022.
Article in English | EMBASE | ID: covidwho-1967393

ABSTRACT

Introduction: Pivotal anti-SARS-CoV-2 vaccines clinical trials did not include patients with immune-mediated conditions such as inflammatory bowel disease (IBD). We aimed to describe the implementation of anti-SARS-CoV-2 vaccines among IBD patients, patients' concerns before vaccination and side-effect profile of the anti-SARS-CoV-2 vaccines using real-world data. Methods: An anonymous web-based self-completed survey was distributed in 36 European countries between June and July 2021. The results of patients' characteristics, concerns, vaccination status and side-effect profile were analysed using descriptive statistics and logistic regression. Results: Among the 3272 IBD patients completing the survey (0.1% of the IBD European population), 79.6% had received at least one dose of anti-SARS-CoV- 2 vaccine, and 71.7% had completed the vaccination process. Most of the patients (70.6%) were vaccinated with the Pfizer-BioNTech (BNT162b2) vaccine. Patients over 60 years old had a significantly higher rate of vaccination (OR 2.98, 95% CI 2.20-4.03, p<0.001). Patients' main concerns before vaccination were the possibility of having worse vaccine-related adverse events due to their IBD (24.6%), having an IBD flare after vaccination (21.1%) and reduced vaccine efficacy due to IBD or associated immunosuppression (17.6%). After the first dose of the vaccine, 72.4% had local symptoms at the injection site and 51.4% had systemic symptoms (5 patients had non-specified thrombosis). Adverse events were less frequent after the second dose of the vaccine and in older patients. When comparing with previous studies from the general population, the IBD patients answering the survey did not seem to have increased side effects (table 1). Only a minority of the patients were hospitalized (0.3%), needed a consultation (3.6%) or had to change IBD therapy (13.4%) after anti- SARS-CoV-2 vaccination. Conclusion: Although IBD patients raised concerns about the safety and efficacy of anti-SARS-CoV-2 vaccines, the implementation of vaccination in those responding to our survey was high and the adverse events were comparable to the general population, with minimal impact on their IBD. (Table Presented)

2.
Malta Medical Journal ; 33(2):49-59, 2021.
Article in English | Scopus | ID: covidwho-1749331

ABSTRACT

BACKGROUND The global pandemic of COVID-19 has brought significant changes all over the world, including Malta. These changes might have impacted people’s health and their lifestyle. Such changes might have limited health and fitness behaviours such as frequency of exercise, intensity of exercise and water intake. Therefore, this study aims to examine and explore how the COVID-19 pandemic has impacted fitness behaviours amongst a sample of the Maltese population. METHODS The sample (n=995) was selected through convenience sampling. Data was collected through an online 38-item survey which was dispersed on social media during April and May 2020. The questions measured the frequency of health behaviours to provide a comparison between the participant’s health behaviours in November 2019 and April 2020, during the COVID-19 pandemic. RESULTS The data was analysed through Factor Analysis which was conducted for dimension reduction. Factor analysis resulted in one factor composed of three variables (frequency of exercise, intensity of exercise and water consumption). Further analyses were conducted using a paired samples t-test on SPSS. Following analysis, the results showed that there was an increase in exercise frequency amongst the sample population, whereas there was a decrease in exercise intensity and water consumption. These results confirm that there was a change in health behaviours amongst the study’s sample. CONCLUSION This study recommends further investigation as to understand this difference in behaviours and its attributes. This can help inform health behaviours should there be further waves of the pandemic or other lockdowns. © 2021, University of Malta. All rights reserved.

3.
Malta Medical Journal ; 33(2):49-59, 2021.
Article in English | CAB Abstracts | ID: covidwho-1489437

ABSTRACT

Background. COVID-19 has brought significant changes all over the world, including Malta. These changes might have impacted people's health and lifestyle. Such changes might have limited health and fitness behaviours such as frequency of exercise, intensity of exercise and water intake. Therefore, this study aims to examine and explore how the COVID-19 pandemic has impacted fitness behaviours amongst a sample of the Maltese population. Methods. The sample (n = 995)was selected through convenience sampling. Data was collected through an online 38-item survey which was dispersed on social media during April and May 2020. The questions measured the frequency of health behaviours to provide a comparison between the participant's health behaviours in November 2019 and April 2020, during the COVID-19 pandemic. Results. The data was analysed through Factor Analysis which was conducted for dimension reduction. Factor analysis resulted in 1 factor composed of 3 variables (frequency of exercise, intensity of exercise and water consumption). Further analyses were conducted using a paired samples t-test on SPSS. Following analysis, the results showed that there was an increase in exercise frequency amongst the sample population, whereas there was a decrease in exercise intensity and water consumption. These results confirm that there was a change in health behaviours amongst the study's sample. Conclusion. This study recommends further investigation as to understand this difference in behaviours and its attributes. This can help inform health behaviours should there be further waves of the pandemic or other lockdowns.

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