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1.
Ir J Psychol Med ; 38(2): 140-144, 2021 06.
Article in English | MEDLINE | ID: covidwho-2096528

ABSTRACT

India is a de facto continent in the garb of a country. COVID-19 is an unprecedented global pandemic spanning continents. Being the second most populous country in the world, experts regard how India deals with the outbreak will have enormous impact on the world's ability to deal with it. The country has been in lockdown since March 25, 2020 until the current time of early May 2020, and despite several challenges, there has been early success. The major conflict now is the health benefits weighed up against the deleterious social and economic consequences of prolonged lockdown, that is, life versus livelihood. This unprecedented calamity could potentially cause or exacerbate various psychiatric disorders. It is recognized that lifestyle changes and limited screen time may help reduce mental health difficulties. Considering the physical barriers to consultation, development of telemedicine services is needed. This pandemic, like other previous pandemics, will pass, and until this happens, we must remain extremely vigilant.


Subject(s)
COVID-19 , Pandemics , Communicable Disease Control , Humans , India/epidemiology , Mental Health , SARS-CoV-2
2.
COVID-19: Tackling Global Pandemics through Scientific and Social Tools ; : 97-107, 2021.
Article in English | Scopus | ID: covidwho-2048799

ABSTRACT

Transmission of coronavirus disease 2019 (COVID-19) is attributed to direct or indirect unguarded contact with infected subjects or inanimate objects. Currently only supportive treatment is available and disease-specific medication or vaccines are yet to be implemented. In such a critical situation, the only choice left is to control the rapid dissemination of the disease through government-enforced strategies and self-imposed precautionary measures across all the afflicted countries around the world. In this chapter, we have appraised in detail the different nonpharmaceutical interventions adapted by government, common people, and health workers to prevent disease spread from one person to another and from one place to another. © 2022 Elsevier Inc. All rights reserved.

3.
Current Research in Nutrition and Food Science ; 10(2):458-475, 2022.
Article in English | Scopus | ID: covidwho-2030349

ABSTRACT

Tea harbours more than 700 bioactive compounds viz, different classes of polyphenols, unique amino acid L-Theanine, alkaloids (Caffeine, Theobromine), and Volatile Flavor Compounds (VFC). Tea's polyphenols make its inherent therapeutic potential unlimited. Tea's significance in managing cancer, diabetes, stomach ulcer, influenza, neurological diseases, etc. is well-documented. However, advantageous biochemical capabilities of tea have yet to be fully utilised. Hence, this review aims at to examine tea's variety, drinking habits, biochemistry, and therapeutic qualities. A number of significant online resources, including Google Scholar, Pub Med, Science Direct, and others, were searched for various research works on tea and its health-promoting qualities by using keywords like tea, health benefits, bioactive components against diseases, etc. Current review highlighted that drinking a cup or more green tea is recommended for improving antioxidant status and to manage diabetes and obesity related problem. However after detailed review work on tea it become clear that not only green tea but also other varies of tea like black, white tea are also harbour lots of bioactive molecules since they are processed from same plant. Tea improves antioxidant status and manages diabetes and obesity. It also helps prevent and cure heart disease, malignancy, digestive dysfunction, and metabolic disorders including obesity and diabetes. Epigallocatechin Gallate (EGCG), found in tea, has been shown to reduce complications from Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-COV 2) infection. When taken in its traditional form to manage ailments, tea is sometimes controversial due to a lack of confirming evidence of its benefits. The paper covers the numerous health advantages of tea, focusing on the specific components contributing to such benefits, and stresses the value of diverse brewing processes. © 2022 The Author(s). Published by Enviro Research Publishers.

4.
Eur Rev Med Pharmacol Sci ; 26(16): 5991-6003, 2022 Aug.
Article in English | MEDLINE | ID: covidwho-2026361

ABSTRACT

OBJECTIVE: The recent monkeypox disease outbreak is another significant threat during the ongoing COVID-19 pandemic. This viral disease is zoonotic and contagious. The viral disease outbreak is considered the substantial infection possessed by the Orthopoxvirus family species after the smallpox virus' obliteration, a representative of the same family. It has potentially threatened the Republic of Congo's regions and certain African subcontinent zones. Although repeated outbreaks have been reported in several parts of the world, as conferred from the epidemiological data, very little is explored about the disease landscape. Thus, here we have reviewed the current status of the monkeypox virus along with therapeutic options available to humanity. MATERIALS AND METHODS: We have accessed and reviewed the available literature on the monkeypox virus to highlight its epidemiology, pathogenicity, virulence, and therapeutic options available. For the review, we have searched different literature and database such as PubMed, PubMed Central, Google Scholar, Web of Science, Scopus, etc., using different keywords such as "monkeypox", "Orthopox", "smallpox", "recent monkeypox outbreak", "therapeutic strategies", "monkeypox vaccines", etc. This review has included most of the significant references from 1983 to 2022. RESULTS: It has been reported that the monkeypox virus shows a remarkable similarity with smallpox during the ongoing outbreak. Sometimes, it creates considerable confusion due to misdiagnosis and similarity with smallpox. The misdiagnosis of the disease should be immediately corrected by rendering some cutting-edge techniques especially intended to isolate the monkeypox virus. The pathophysiology and the histopathological data imply the immediate need to design effective therapeutics to confer resistance against the monkeypox virus. Most importantly, the potential implications of the disease are not given importance due to the lack of awareness programs. Moreover, specific evolutionary evidence is crucial for designing effective therapeutic strategies that confer high resistance, particularly against this species. CONCLUSIONS: The review focuses on a brief overview of the recent monkeypox virus outbreak, infection biology, epidemiology, transmission, clinical symptoms, and therapeutic aspects. Such an attempt will support researchers, policymakers, and healthcare professionals for better treatment and containment of the infection caused by the monkeypox virus.


Subject(s)
COVID-19 , Monkeypox , Vaccines , COVID-19/epidemiology , Disease Outbreaks/prevention & control , Humans , Monkeypox/diagnosis , Monkeypox/drug therapy , Monkeypox/epidemiology , Monkeypox virus , Pandemics
5.
NeuroQuantology ; 20(7):1107-1117, 2022.
Article in English | EMBASE | ID: covidwho-1969823

ABSTRACT

Providing medical care over long distances using communication systems and advanced technologies is called "telemedicine." In recent years, dentistry has witnessed a substantial amount of technological advancement. The utilization of computers, telecommunication technology, digital diagnostic imaging services, equipment, and software for analysis and follow-up have all seen significant advancements in recent years because of developments in information technology. The field of dentistry has progressed to a point where it can now cover far greater distances than it was previously capable of. In 1997, "TD" was coined to describe "the practice of employing video conferencing technologies to diagnose and provide advice regarding treatment across a distance." It provides consultations over long distances using electronic medical records, the internet, information, and communication technology. TD has four potential applications. These are teleconsultation, Tele-education, telemonitoring, and telesurgery. TD can also be used to monitor patients remotely. A general dentist in a rural region can communicate with a specialist for advice through teleconsultation by sending either live patient data or patient medical records to the specialist. This allows the dentist to provide better care for their patients. Remote rural practitioners can acquire continuous medical education using interactive video conferencing and web-based self-instruction. In telemonitoring, patients record and send data to doctors via phone, fax, or the internet. Continuous data collection and automated transmission of that data to another physician involved in the care of the patients is another method that may be used to assess the condition of the patients. Telesurgery allows experts in metropolitan regions to assist surgeons located in rural or distant places through the use of video and audio links made possible by the internet. This ensures that patients receive the best possible surgical care. This technology makes it possible for multiple dental practitioners to work together to arrive at an accurate diagnosis and a suitable treatment plan for patients who are seen in locations with a shortage of dentists or dental specialists or where dental specialists are not readily available. As a result, the objective of this study is to explore the development of tele dentistry and how it might be used in practice to address the disparities in oral health care between rural and urban areas.

6.
BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY ; 129:149-149, 2022.
Article in English | Web of Science | ID: covidwho-1904900
7.
BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY ; 129:141-141, 2022.
Article in English | Web of Science | ID: covidwho-1904858
8.
Medical Internet of Things: Techniques, Practices and Applications ; : 147-159, 2021.
Article in English | Scopus | ID: covidwho-1902559

ABSTRACT

When treating cardiac patients, the most important factors for doctors and the healthcare system are monitoring or diagnosis of the patient when required or sometimes continuously. Cardiac patients often have trouble visiting healthcare centers for their treatment. Patients living in remote places face more difficulties in this respect. Moreover, during the COVID-19 pandemic, such patients needed to avoid contact with others. As a whole, remote diagnostic or remote treatment facilities are the need of the hour, and Medical Internet of Things (MIoT) is the feasible solution to this situation. MIoT is equipped with wearable devices and remote or internet-based connection with healthcare information systems. This chapter explores application of an MIoT-based infrastructure for the treatment of cardiac patients. Possibilities explored are using various wearable sensors, devices and transmission;storing patient records and then analyzing the patient data;disease prediction;and decisions supporting or generating automatic alarms based on a patient’s deterioration. © 2022 Taylor & Francis Group, LLC.

9.
Physics of Fluids ; 34(6), 2022.
Article in English | Scopus | ID: covidwho-1890393

ABSTRACT

A face mask is essential personal protective equipment to mitigate the spread of COVID-19. While a cloth mask has the least ability to prevent the passage of infectious respiratory droplets through it compared to surgical and N95 masks, the surgical mask does not fit snugly and causes significant air leakage. The synthetic fibers in the latter reduce comfortability and are an allergen for facial eczema. Moreover, the N95 mask causes CO2 inhalation and reduces heat transfer in the nose. Therefore, the objective of the present work is to improve the effectiveness of a two-layer cloth mask by introducing an intermediate, high-efficiency particulate air (HEPA) filter layer. A significant volume of impacted droplets penetrates through a single-layer cloth mask, ejecting secondary droplets from the rear side. However, a two-layer cloth mask prevents this ejection. Despite slowing down the liquid penetration, capillary imbibition through cloth due to its hydrophilicity causes the transport of the liquid into the second layer, resulting in a thin-liquid layer at the mask's rear-side surface and contaminating it. Conversely, the HEPA filter inserted in the cloth mask prevents the imbibition, making the second cloth layer free of contamination. We attribute the impedance to the imbibition by the intermediate HEPA filter layer to its hydrophobic characteristics. We experimentally and analytically assess the role of wettability on capillary imbibition. The breathability measurements of masks show that the HEPA inserted in the cloth mask does not reduce its breathability compared to that of the surgical mask. © 2022 Author(s).

10.
Journal of the American College of Cardiology ; 79(9):2370-2370, 2022.
Article in English | Web of Science | ID: covidwho-1849462
11.
Journal of Family Business Management ; : 22, 2022.
Article in English | Web of Science | ID: covidwho-1816418

ABSTRACT

Purpose This study assesses the capability of artificial intelligence integrated customer relationship management (AI-CRM) technology for sustaining family businesses in times of crisis, such as the COVID-19 pandemic. The study also investigates the moderating role of strategic intent in sustaining family businesses in times of crisis. Design/methodology/approach The authors used dynamic capability view theory and related literature on family business and technology adoption to develop a conceptual model. This model has been validated using the structural equation modeling technique considering 332 usable responses from people of India involved in family businesses and technology adoption. The study also uses multigroup analysis to examine the moderating role of strategic intent. Findings The study finds that adoption of AI-CRM technology significantly and positively impacts dynamic capabilities of the family businesses, such as sensing, seizing and transforming capabilities, which in turn positively and significantly influences their sustainability during crises. The study also highlights the significant moderating impact of strategic intent for sustaining family business firms in uncertain times. Practical implications This study has highlighted the importance for family businesses to adopt AI-CRM technology and its influence on their dynamic capabilities. The study also provides important inputs to the management of family businesses regarding adoption of new technologies and their significance during crises. The study also documents that strategic intent could help family businesses to survive during such times. The study is conducted in India and thus cannot be generalized. Originality/value This study table is unique in that it investigates the influence of AI-CRM technology and the moderating role of strategic intent on family business sustainability in times of crisis. Moreover, the proposed theoretical model is a unique model with explanative power of 71%.

12.
Statistics and Public Policy ; 9(1):74-84, 2022.
Article in English | Web of Science | ID: covidwho-1815730

ABSTRACT

We assess the treatment effect of juvenile stay-at-home orders (JSAHO) on reducing the rate of SARS-CoV-2 infection spread in Saline County ("Saline"), Arkansas, by examining the difference between Saline's and control Arkansas counties' changes in daily and mean log infection rates of pretreatment (March 28-April 5, 2020) and treatment periods (April 6-May 6, 2020). A synthetic control county is constructed based on the parallel-trends assumption, least-squares fitting on pretreatment and socio-demographic covariates, and elastic-net-based methods, from which the counterfactual outcome is predicted and the treatment effect is estimated using the difference-in-differences, the synthetic control, and the changes-in-changes methodologies. Both the daily and average treatment effects of JSAHO are shown to be significant. Despite its narrow scope and lack of enforcement for compliance, JSAHO reduced the rate of the infection spread in Saline. Supplementary materials for this article are available online.

13.
Feminist Studies ; 47(3):599-626, 2021.
Article in English | Scopus | ID: covidwho-1793662
14.
International Political Economy Series ; : 133-161, 2022.
Article in English | Scopus | ID: covidwho-1767444

ABSTRACT

The COVID-19 pandemic has brought to the forefront the vulnerability of the most marginalized populations, thus exposing the faultlines in neoliberal governance. Be it immigrants in the US, domestic migrant workers in India or violence against black bodies in western democracies, the pandemic has now enthused academics to think about the role of precarity and the resultant differential distribution of resources across the world. Amidst this, sex workers have been hard hit. On April 8, 2020 UNAIDS released a press statement asserting that as already criminalized, marginalized and living in financial precarity, ‘sex workers must not be left behind in the response to COVID-19’ (UNAIDS, Sex workers must not be left behind in the response to COVID-19, 2020). Yet, sex work precarity is by no means recent phenomenon. Sex work has been, for a long time, theorized as precarious labor and sex workers as precarious bodies. Sexual labor posits the body at the center stage of neoliberal biopolitics, whereby commodification, consumption and controlling of precarious bodies go hand-in-hand with and become integral for preserving the gendered/racialized neoliberal body politic. Thus, sexually precarious bodies become the site for several legal and pathological securitization initiatives. © 2022, The Author(s), under exclusive license to Springer Nature Switzerland AG.

15.
Endothelial Signaling in Vascular Dysfunction and Disease: From Bench to Bedside ; : 205-211, 2021.
Article in English | Scopus | ID: covidwho-1750913

ABSTRACT

The most commonly reported symptoms by patients affected by coronavirus disease 2019 (COVID-19) are fatigue, fever, and respiratory distress. However, other major changes observed in COVID-19 patients such as high blood pressure, thrombosis, and pulmonary embolism seem to suggest that the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is targeting the endothelium, one of the largest organs in the human body. This chapter reports on the role of the endothelium as a target of SARS-CoV-2. © 2021 Elsevier Inc. All rights reserved.

16.
PubMed; 2021.
Preprint in English | PubMed | ID: ppcovidwho-329620

ABSTRACT

Background: Hyperinflammation is a key event that occurs with SARS-CoV-2 infection. In the lung, hyperinflammation leads to structural damage to tissue. To date, numerous lung histological studies have shown extensive alveolar damage, but there is scarce documentation of vascular inflammation in postmortem lung tissue.

17.
Management Decision ; 2022.
Article in English | Scopus | ID: covidwho-1713936

ABSTRACT

Purpose: The purpose of this study is to identify the critical success factors (CSFs) of corporate social responsibility (CSR) in the post-COVID-19 period and to identify the cause–effect relationships amongst those CSFs. Design/methodology/approach: The success factors impacting CSR activities are identified based on inputs from 14 experts in the CSR domain. Thereafter, authors use a statistical approach to identify CSFs with inputs from useable respondents. Finally, the Decision-Making Trial and Evaluation Laboratory (DEMATEL) method was applied to understand the causal relationship between different CSFs. Findings: Using the DEMATEL method, the authors developed an analytical model showing cause–effect aspects of the CSFs and identified seven factors which firms need to emphasize more to execute better CSR activities in the post-COVID-19 period. Research limitations/implications: The authors asked 14 experts for their inputs, but more experts could have made identifying success factors more comprehensive. In this study, the DEMATEL method found seven CSFs that improve CSR activities in the post-COVID-19 period. Another identification process could have enriched the study. The findings of this study cannot be generalized since this study is based on the inputs of employees from India only. Practical implications: This proposed analytical model is effective in determining the complex interactions among all impacting CSFs. Firms' CSR managers and policy makers can use the proposed model, especially in the post-COVID-19 period. Originality/value: The proposed model provides a precise and most accurate analysis for CSFs impacting CSR activities in the post-COVID-19 period. It also provides a unique opportunity for the competent authorities at firms to understand the interaction of different impacting CSFs and takes necessary actions. No other exhaustive analytical model is available in this context. © 2022, Emerald Publishing Limited.

18.
Int J Tuberc Lung Dis ; 26(3): 285-287, 2022 03 01.
Article in English | MEDLINE | ID: covidwho-1707991
19.
Embase;
Preprint in English | EMBASE | ID: ppcovidwho-326810

ABSTRACT

Emergence of SARS-CoV-2 as a serious pandemic has altered the global socioeconomic dynamics. The wide prevalence, high death counts and rapid emergence of new variants urge for establishment of research infrastructure to facilitate rapid development of efficient therapeutic modalities and preventive measures. In agreement with this, five SARS-CoV2 strains (ILS01, ILS02, ILS03, ILS15 and ILS24) of four different clades (19A, 19B, 20A and 20B) were isolated from patient swab samples collected during the 1stCOVID-19 wave in Odisha, India. The viral isolates were adapted to in-vitro cultures and further characterized to identify strain specific variations in viral growth characteristics. All the five isolates showed substantial amount of virus induced CPE however ILS03 belonging to 20A clade displayed highest level of CPE. Time kinetics experiment revealed spike protein expression was evident after 16th hours post infection in all five isolates. ILS03 induced around 90% of cytotoxicity. Further, the susceptibility of various cell lines (human hepatoma cell line (Huh-7), CaCo2 cell line, HEK-293T cells, Vero, Vero-E6, BHK-21, THP-1 cell line and RAW 264.7 cells) were assessed. Surprisingly, it was found that the human monocyte cells THP-1 and murine macrophage cell line RAW 264.7 were permissive to all the SARS-CoV-2 isolates. The neutralization susceptibility of viral isolates to vaccine-induced antibodies was determined using sera from individuals vaccinated in the Government run vaccine drive in India. The micro-neutralization assay suggested that both Covaxin and Covishield vaccines were equally effective (100% neutralization) against all of the isolates. The whole genome sequencing of culture adapted viral isolates and viral genome from patient oropharyngeal swab sample suggested that repetitive passaging of SARS-CoV2 virus in Vero-E6 cells did not lead to emergence of many mutations during the adaptation in cell culture. Phylogenetic analyses revealed that the five isolates clustered to respective clades. The major goal was to isolate and adapt SARS-CoV-2 viruses in in-vitro cell culture with minimal modification to facilitate research activities involved in understanding the molecular virology, host-virus interactions, application of these strains for drug discovery and animal challenge models development which eventually will contribute towards the development of effective and reliable therapeutics.

20.
EuropePMC; 2020.
Preprint in English | EuropePMC | ID: ppcovidwho-323102

ABSTRACT

Robust testing and tracing are key to fighting the menace of coronavirus disease 2019 (COVID-19). This outbreak has progressed with tremendous impact on human life, society and economy. In this paper, we propose an age-structured SIQR model to track the progression of the pandemic in India, Italy and USA, taking into account the different age-structures of these countries. We have made predictions about the disease dynamics, identified the most infected age-groups and analysed the effectiveness of social distancing measures taken in the early stages of infection. The basic reproductive ratio R 0 has been numerically calculated for each country.We propose a strategy of age-targeted testing, with increased testing in the most proportionally infected age-groups. We observe a marked flattening of the infection curve upon simulating increased testing in the 15-40 year age-groups in India. Thus, we conclude that social distancing and widespread testing are effective methods of control, with emphasis on testing and identifying the hotspots of highly infected populations.

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