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Revista Medica de Chile ; 148(10):1467-1474, 2020.
Article in Spanish | GIM | ID: covidwho-1080061


Coronavirus disease 19 is characterized by an intense inflammatory response and a high incidence of thrombotic events. Autopsy studies show severe endothelial injury associated with thrombosis of the alveolar capillaries of the lungs and other organs. In the pathophysiology of this disease endothelial injury and dysfunction, inflammation and thrombosis are key factors for the development of severe phenotypes. Therefore, we should consider this entity as a systemic endothelial disease in which an obstructive microvascular syndrome secondary to an intense thrombo-inflammatory response leads to acute respiratory insufficiency and multiorgan failure. Heparin is an excellent drug to treat Covid-19 patients due to its anticoagulant, anti-inflammatory, antiviral and endothelial effects. Clinical guidelines agree that the use of heparin thromboprophylaxis is a component of Covid-19 coagulopathy treatment, even though the dose and duration of treatments are not well defined.

Rivista Di Psicologia Dell Emergenza E Dell Assistenza Umanitaria ; - (23):30-35, 2020.
Article in Italian | Web of Science | ID: covidwho-1001071


In this article, the authors aim to describe the Covid-19 toll-free psychological helpline activated by Azienda Regionale Ares 118 during the SARS-Cov-2 coronavirus emergency. The article highlights the peculiarity of Ares 118's choice to structure the service by exclusively engaging qualified psychologists belonging to Lazio's main associations of emergency psychology, making them work in close collaboration with the medical staff of the same toll-free number. The article is the result of what has been observed in the first three months since the activation of the service and contains, in addition to the summary of the types of requests received, the strengths and needed improvements of what can be considered an innovative and functioning model that provides concrete and useful responses to citizens during the emergency. In this article it has not been possible to process the statistical data collected, as the service is still active and the data collection is ongoing. The final considerations provide possible scenarios of integrated psychology services in the context of regional or national health systems, paving the way for what could be a constant and consolidated reality.

AJNR Am J Neuroradiol ; 41(12): 2206-2208, 2020 12.
Article in English | MEDLINE | ID: covidwho-724225


We describe the case of a 63-year-old woman who developed a coronavirus disease 2019-associated acute encephalopathy with perivascular gadolinium enhancement.

COVID-19/complications , Posterior Leukoencephalopathy Syndrome/pathology , Posterior Leukoencephalopathy Syndrome/virology , Contrast Media , Female , Gadolinium , Humans , Magnetic Resonance Imaging/methods , Middle Aged , Posterior Leukoencephalopathy Syndrome/diagnostic imaging , SARS-CoV-2