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Yakut Medical Journal ; - (3):113-116, 2022.
Article in English | Web of Science | ID: covidwho-2243114


The article presents a clinical case of multisystem inflammatory syndrome as a relsult of a new coronavirus infection in a 7 months old child. The clinical picture is similar to Kawasaki syndrome.

Yakut Medical Journal ; - (3):56-59, 2022.
Article in English | Web of Science | ID: covidwho-2238859


Gastrointestinal tract damage is a part of the course of multisystem inflammatory syndrome in children (MVS-D) associated with the new COVID-19 coronavirus infection. According to the results of a retrospective study, gastrointestinal tract damage was detected in 77% of patients with MVS-D and is represented by signs such as abdominal pain, vomiting, diarrhea and peritoneal symptoms. In children with gastrointestinal tract lesions, significant differences were noted in the frequency of occurrence of the following signs: hepatomegaly, splenomegaly, hypotension/shock, as well as conjunctivitis and facial swelling. Among laboratory abnormalities, hypoalbuminemia is more characteristic, but the level of CRP and troponin is higher. The article shows that gastrointestinal tract damage is an important early predictor of the severity of MVS-D.

Yakut Medical Journal ; - (3):105-107, 2021.
Article in English | Web of Science | ID: covidwho-1561709


Generally, COVID-19 is milder in children than in adults. But already in May 2020, information about a multisystem inflammatory disease that affects children and adolescents began to arrive from around the world. The pathogenesis and pathological picture of COVID-19 are characterized by the development of thrombus inflammation, generalized microangiopathy in the form of destructive-proliferative viral vasculitis and coagulopathy with secondary damage to the skin, internal organs, central nervous system, hemophagocytosis. This paper presents the observation of ten patients aged from 6 months to 14 years treated at the Children's Clinical Infectious Diseases Hospital in Yakutsk from September 2020 to March 2021 with a diagnosis of U07.2 - Coronavirus infection caused by.OVID- 19, no virus identified, M30.3 Kawasaki-like syndrome. The presence of prolonged fever, damage to two and whiter systems of the body, laboratory markers of inflammation without obvious foci of an acute infectious process was the criteria for making a diagnosis. Also, a prerequisite for establishing a diagnosis was the presence of contact with patients with COVID-19 or antibodies to SARS-CoV-2. There were no patients with complicated cases that required intensive care among the observed patients, but there were severe cardiac lesions in some children. All our patients were of Yakut nationality. In contrast to the available literature data, we did not observe a significant violation of the blood coagulation system;in some patients, thrombocytosis was prominent. We observed a subarachnoid haemorrhage in one patient.